Boc-Val-Ala-PAB-PNP
Based on 1 Customer Validation
Boc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.62%
- CAS No.: 1884578-00-0
- 화학식: C27H34N4O9
- 분자량:558.58
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Protease Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1884578-00-0
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Appearance Solid
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분자량 558.58
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화학식 C27H34N4O9
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Color White to light yellow
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SMILES
CC([C@H](NC(OC(C)(C)C)=O)C(N[C@H](C(NC1=CC=C(C=C1)COC(OC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)C)=O)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 35 mg/mL (62.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7903 mL | 8.9513 mL | 17.9025 mL | 44.7563 mL |
| 5 mM | 0.3581 mL | 1.7903 mL | 3.5805 mL | 8.9513 mL | |
| 10 mM | 0.1790 mL | 0.8951 mL | 1.7903 mL | 4.4756 mL | |
| 15 mM | 0.1194 mL | 0.5968 mL | 1.1935 mL | 2.9838 mL | |
| 20 mM | 0.0895 mL | 0.4476 mL | 0.8951 mL | 2.2378 mL | |
| 25 mM | 0.0716 mL | 0.3581 mL | 0.7161 mL | 1.7903 mL | |
| 30 mM | 0.0597 mL | 0.2984 mL | 0.5968 mL | 1.4919 mL | |
| 40 mM | 0.0448 mL | 0.2238 mL | 0.4476 mL | 1.1189 mL | |
| 50 mM | 0.0358 mL | 0.1790 mL | 0.3581 mL | 0.8951 mL | |
| 60 mM | 0.0298 mL | 0.1492 mL | 0.2984 mL | 0.7459 mL |
Boc-Val-Ala-PAB-PNP Related Classifications
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