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Referencia número: HY-126894

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Bis-PEG9-acid

Name: Bis-PEG9-acid
Brand: MedChemExpress
SKU: HY-126894
Price: 61.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Bis- PEG9- acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis- PEG9- acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 97.0%
No. CAS: 1268488-70-5
Fòrmula: C₂₂H₄₂O₁₃
Peso molecular:514.56

Almacenamiento:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Bis-PEG9-acid Chemical Structure

No. CAS: 1268488-70-5

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Bis- PEG9- acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis- PEG9- acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

IC₅₀ & Target^[1]

PEGs	Cleavable Linker

Ver todos los productos específicos de isoformas PROTAC Linkers :

Ver todos los productos específicos de isoformas ADC Linkers :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 1268488-70-5
Appearance Solid
Peso molecular 514.56
Fòrmula C₂₂H₄₂O₁₃
Color White to off-white
SMILES

O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Bach A, et al. Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDAreceptor interaction. Angew Chem Int Ed Engl. 2009;48(51):9685-9. [Content Brief]

[2]. Norbert Basler, et al. Nucleoside-triphosphate conjugate and methods for the use thereof. WO2012150035A1.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias

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Nombre del producto:
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Bis-PEG9-acid

Bis-PEG7-acid

Bis-PEG10-acid

Bis-PEG2-acid

Bis-PEG5-acid

Bis-PEG6-acid

Bis-PEG1-acid

Bis-PEG4-acid

Bis-PEG3-acid

Bis-PEG8-acid

Ver todos los productos específicos de isoformas PROTAC Linkers

Ver todos los productos específicos de isoformas ADC Linkers

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Bioz

Bis-PEG9-acid

Bis-PEG7-acid

Bis-PEG10-acid

Bis-PEG2-acid

Bis-PEG5-acid

Bis-PEG6-acid

Bis-PEG1-acid

Bis-PEG4-acid

Bis-PEG3-acid

Bis-PEG8-acid

Ver todos los productos específicos de isoformas PROTAC Linkers

Ver todos los productos específicos de isoformas ADC Linkers

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Bis-PEG9-acid Related Classifications

HY-126894 Related Classifications

Bioz