Val-Cit-PAB-Exatecan TFA
Based on 1 Customer Validation
Val-Cit-PAB-Exatecan (Val-Cit-PAB-DX8951) TFA is a agent-linker conjugate for ADC. Val-Cit-PAB-Exatecan TFA is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 2928571-44-0
- Formula: C45H50F4N8O11
- Molecular Weight:954.92
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2928571-44-0
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Appearance Solid
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Molecular Weight 954.92
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Formula C45H50F4N8O11
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Color Light yellow to yellow
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SMILES
CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC(C=C1)=CC=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O.O=C(O)C(F)(F)F
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Synonyms
Val-Cit-PAB-DX8951 TFA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (104.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0472 mL | 5.2360 mL | 10.4721 mL | 26.1802 mL |
| 5 mM | 0.2094 mL | 1.0472 mL | 2.0944 mL | 5.2360 mL | |
| 10 mM | 0.1047 mL | 0.5236 mL | 1.0472 mL | 2.6180 mL | |
| 15 mM | 0.0698 mL | 0.3491 mL | 0.6981 mL | 1.7453 mL | |
| 20 mM | 0.0524 mL | 0.2618 mL | 0.5236 mL | 1.3090 mL | |
| 25 mM | 0.0419 mL | 0.2094 mL | 0.4189 mL | 1.0472 mL | |
| 30 mM | 0.0349 mL | 0.1745 mL | 0.3491 mL | 0.8727 mL | |
| 40 mM | 0.0262 mL | 0.1309 mL | 0.2618 mL | 0.6545 mL | |
| 50 mM | 0.0209 mL | 0.1047 mL | 0.2094 mL | 0.5236 mL | |
| 60 mM | 0.0175 mL | 0.0873 mL | 0.1745 mL | 0.4363 mL | |
| 80 mM | 0.0131 mL | 0.0655 mL | 0.1309 mL | 0.3273 mL | |
| 100 mM | 0.0105 mL | 0.0524 mL | 0.1047 mL | 0.2618 mL |
Val-Cit-PAB-Exatecan TFA Related Classifications
HY-153031A Related Classifications
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