BCN-HS-PEG2-bis(PNP)
BCN-HS-PEG2-bis(PNP) is a p-nitrophenyl ADC linker that can be used for further coupling of ADC toxins with peptide linkers. BCN-HS-PEG2-bis(PNP) can be combined with vc-PABC-MMAE (HY-15162) to form drug-linker conjugates for ADCs.
For research use only. We do not sell to patients.
- CAS No.: 2126749-95-7
- Formula: C34H39N5O17S
- Molecular Weight:821.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
BCN-HS-PEG2-bis(PNP) (Compound 62) is a bioconjugation linker reagent comprising a bicyclo[6.1.0]nonyne (BCN) group, sulfamide (HS) moiety, diethylene glycol (PEG2) spacer, and bis(p-nitrophenyl) (PNP) activated ester groups[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2126749-95-7
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Molecular Weight 821.76
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Formula C34H39N5O17S
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SMILES
O=[N+]([O-])C(C=C1)=CC=C1OC(OCCN(CCOC(OC2=CC=C(C=C2)[N+]([O-])=O)=O)C(OCCOCCNS(NC(OC[C@H]3[C@]4([H])[C@@]3([H])CCC#CCC4)=O)(=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BCN-HS-PEG2-bis(PNP) Related Classifications
HY-158199 Related Classifications
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