Mal-PEG2-Val-Cit-PABA
Based on 1 Customer Validation
Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.91%
- CAS No.: 1662687-83-3
- Formula: C27H38N6O9
- Molecular Weight:590.63
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Protease Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1662687-83-3
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Appearance Solid
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Molecular Weight 590.63
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Formula C27H38N6O9
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Color White to off-white
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SMILES
OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCN2C(C=CC2=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (211.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6931 mL | 8.4655 mL | 16.9311 mL | 42.3277 mL |
| 5 mM | 0.3386 mL | 1.6931 mL | 3.3862 mL | 8.4655 mL | |
| 10 mM | 0.1693 mL | 0.8466 mL | 1.6931 mL | 4.2328 mL | |
| 15 mM | 0.1129 mL | 0.5644 mL | 1.1287 mL | 2.8218 mL | |
| 20 mM | 0.0847 mL | 0.4233 mL | 0.8466 mL | 2.1164 mL | |
| 25 mM | 0.0677 mL | 0.3386 mL | 0.6772 mL | 1.6931 mL | |
| 30 mM | 0.0564 mL | 0.2822 mL | 0.5644 mL | 1.4109 mL | |
| 40 mM | 0.0423 mL | 0.2116 mL | 0.4233 mL | 1.0582 mL | |
| 50 mM | 0.0339 mL | 0.1693 mL | 0.3386 mL | 0.8466 mL | |
| 60 mM | 0.0282 mL | 0.1411 mL | 0.2822 mL | 0.7055 mL | |
| 80 mM | 0.0212 mL | 0.1058 mL | 0.2116 mL | 0.5291 mL | |
| 100 mM | 0.0169 mL | 0.0847 mL | 0.1693 mL | 0.4233 mL |
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