Norbornene-NHS
Based on 1 Customer Validation
Norbornene-NHS is a norbornene-functionalized antibody-drug conjugate linker (ADC Linker) bearing an NHS ester, which is applicable for highly efficient and specific antibody conjugation reactions in ADC research and development. Norbornene-NHS also acts as an azide-group-containing click chemistry reagent, serving as a dienophile for copper-free click reaction conjugation.
For research use only. We do not sell to patients.
- Purity: 92.08%
- CAS No.: 1888335-48-5
- Formula: C12H13NO5
- Molecular Weight:251.24
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Norbornene-NHS (1 h) efficiently couples to Fmoc-deprotected proteasome inhibitor scaffold 6 in DMF with DIPEA to produce norbornene-functionalized proteasome inhibitor Nor-Ahx3L3VS 8 in 94% yield[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1888335-48-5
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Appearance Liquid (Density: 1.42±0.1 g/cm3)
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Molecular Weight 251.24
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Formula C12H13NO5
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Color Light yellow to yellow
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SMILES
O=C(OC1CC2C=CC1C2)ON3C(CCC3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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