PTAD-PEG8-alkyne
Based on 1 Customer Validation
PTAD-PEG8-alkyne is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Formula: C31H48N4O13
- Molecular Weight:684.73
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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Appearance Oil
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Molecular Weight 684.73
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Formula C31H48N4O13
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SMILES
COC1=C(OCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCC#C)=O)C=CC(N2C(NNC2=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (182.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (263 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4604 mL | 7.3021 mL | 14.6043 mL | 36.5107 mL |
| 5 mM | 0.2921 mL | 1.4604 mL | 2.9209 mL | 7.3021 mL | |
| 10 mM | 0.1460 mL | 0.7302 mL | 1.4604 mL | 3.6511 mL | |
| 15 mM | 0.0974 mL | 0.4868 mL | 0.9736 mL | 2.4340 mL | |
| 20 mM | 0.0730 mL | 0.3651 mL | 0.7302 mL | 1.8255 mL | |
| 25 mM | 0.0584 mL | 0.2921 mL | 0.5842 mL | 1.4604 mL | |
| 30 mM | 0.0487 mL | 0.2434 mL | 0.4868 mL | 1.2170 mL | |
| 40 mM | 0.0365 mL | 0.1826 mL | 0.3651 mL | 0.9128 mL | |
| 50 mM | 0.0292 mL | 0.1460 mL | 0.2921 mL | 0.7302 mL | |
| 60 mM | 0.0243 mL | 0.1217 mL | 0.2434 mL | 0.6085 mL | |
| 80 mM | 0.0183 mL | 0.0913 mL | 0.1826 mL | 0.4564 mL | |
| 100 mM | 0.0146 mL | 0.0730 mL | 0.1460 mL | 0.3651 mL |