OH-Glu-Val-Cit-PAB-MMAE
Based on 1 Customer Validation
OH-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (OH-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.03%
- CAS No.: 1895916-23-0
- Formula: C63H100N10O15
- Molecular Weight:1237.53
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 1895916-23-0
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Appearance Solid
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Molecular Weight 1237.53
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Formula C63H100N10O15
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC(O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 180 mg/mL (145.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8081 mL | 4.0403 mL | 8.0806 mL | 20.2015 mL |
| 5 mM | 0.1616 mL | 0.8081 mL | 1.6161 mL | 4.0403 mL | |
| 10 mM | 0.0808 mL | 0.4040 mL | 0.8081 mL | 2.0202 mL | |
| 15 mM | 0.0539 mL | 0.2694 mL | 0.5387 mL | 1.3468 mL | |
| 20 mM | 0.0404 mL | 0.2020 mL | 0.4040 mL | 1.0101 mL | |
| 25 mM | 0.0323 mL | 0.1616 mL | 0.3232 mL | 0.8081 mL | |
| 30 mM | 0.0269 mL | 0.1347 mL | 0.2694 mL | 0.6734 mL | |
| 40 mM | 0.0202 mL | 0.1010 mL | 0.2020 mL | 0.5050 mL | |
| 50 mM | 0.0162 mL | 0.0808 mL | 0.1616 mL | 0.4040 mL | |
| 60 mM | 0.0135 mL | 0.0673 mL | 0.1347 mL | 0.3367 mL | |
| 80 mM | 0.0101 mL | 0.0505 mL | 0.1010 mL | 0.2525 mL | |
| 100 mM | 0.0081 mL | 0.0404 mL | 0.0808 mL | 0.2020 mL |
OH-Glu-Val-Cit-PAB-MMAE Related Classifications
HY-148245 Related Classifications
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