1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. Val-Cit-PAB-MMAE

Val-Cit-PAB-MMAE 

Cat. No.: HY-100374 Purity: 99.83%
Handling Instructions

Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide Val-Cit-PAB.

For research use only. We do not sell to patients.

Val-Cit-PAB-MMAE Chemical Structure

Val-Cit-PAB-MMAE Chemical Structure

CAS No. : 644981-35-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 1780 In-stock
Estimated Time of Arrival: December 31
1 mg USD 420 In-stock
Estimated Time of Arrival: December 31
5 mg USD 1020 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1440 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide Val-Cit-PAB.

IC50 & Target

Auristatin

 

Molecular Weight

1123.43

Formula

C₅₈H₉₄N₁₀O₁₂

CAS No.

644981-35-1

SMILES

CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C)[[email protected]@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C(OCC3=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)N)=O)=O)C=C3)=O)C)=O)=O)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (44.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8901 mL 4.4507 mL 8.9013 mL
5 mM 0.1780 mL 0.8901 mL 1.7803 mL
10 mM 0.0890 mL 0.4451 mL 0.8901 mL
*Please refer to the solubility information to select the appropriate solvent.

Purity: 99.83%

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Val-Cit-PAB-MMAE
Cat. No.:
HY-100374
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