PTAD-PEG8-azide
Based on 1 Customer Validation
PTAD-PEG8-azide is a cleavable ADC linker containing an azide group. PTAD-PEG8-azide can be used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.77%
- Formula: C30H49N7O13
- Molecular Weight:715.75
-
Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Oil
-
Molecular Weight 715.75
-
Formula C30H49N7O13
-
Color Colorless to light yellow
-
SMILES
COC1=C(OCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)C=CC(N2C(NNC2=O)=O)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (174.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (237 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3971 mL | 6.9857 mL | 13.9714 mL | 34.9284 mL |
| 5 mM | 0.2794 mL | 1.3971 mL | 2.7943 mL | 6.9857 mL | |
| 10 mM | 0.1397 mL | 0.6986 mL | 1.3971 mL | 3.4928 mL | |
| 15 mM | 0.0931 mL | 0.4657 mL | 0.9314 mL | 2.3286 mL | |
| 20 mM | 0.0699 mL | 0.3493 mL | 0.6986 mL | 1.7464 mL | |
| 25 mM | 0.0559 mL | 0.2794 mL | 0.5589 mL | 1.3971 mL | |
| 30 mM | 0.0466 mL | 0.2329 mL | 0.4657 mL | 1.1643 mL | |
| 40 mM | 0.0349 mL | 0.1746 mL | 0.3493 mL | 0.8732 mL | |
| 50 mM | 0.0279 mL | 0.1397 mL | 0.2794 mL | 0.6986 mL | |
| 60 mM | 0.0233 mL | 0.1164 mL | 0.2329 mL | 0.5821 mL | |
| 80 mM | 0.0175 mL | 0.0873 mL | 0.1746 mL | 0.4366 mL | |
| 100 mM | 0.0140 mL | 0.0699 mL | 0.1397 mL | 0.3493 mL |