Mal-amide-PEG8-Val-Ala-PAB-PNP
Based on 1 Customer Validation
Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 95.73%
- CAS No.: 2210247-59-7
- Formula: C48H68N6O19
- Molecular Weight:1033.08
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2210247-59-7
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Appearance Viscous Liquid
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Molecular Weight 1033.08
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Formula C48H68N6O19
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Color Colorless to light yellow
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SMILES
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](C)C(NC2=CC=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (96.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9680 mL | 4.8399 mL | 9.6798 mL | 24.1995 mL |
| 5 mM | 0.1936 mL | 0.9680 mL | 1.9360 mL | 4.8399 mL | |
| 10 mM | 0.0968 mL | 0.4840 mL | 0.9680 mL | 2.4199 mL | |
| 15 mM | 0.0645 mL | 0.3227 mL | 0.6453 mL | 1.6133 mL | |
| 20 mM | 0.0484 mL | 0.2420 mL | 0.4840 mL | 1.2100 mL | |
| 25 mM | 0.0387 mL | 0.1936 mL | 0.3872 mL | 0.9680 mL | |
| 30 mM | 0.0323 mL | 0.1613 mL | 0.3227 mL | 0.8066 mL | |
| 40 mM | 0.0242 mL | 0.1210 mL | 0.2420 mL | 0.6050 mL | |
| 50 mM | 0.0194 mL | 0.0968 mL | 0.1936 mL | 0.4840 mL | |
| 60 mM | 0.0161 mL | 0.0807 mL | 0.1613 mL | 0.4033 mL | |
| 80 mM | 0.0121 mL | 0.0605 mL | 0.1210 mL | 0.3025 mL |
Mal-amide-PEG8-Val-Ala-PAB-PNP Related Classifications
HY-148425 Related Classifications
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