Mc-d-Val-d-Cit-PAB-PNP
Based on 1 Customer Validation
Mc-d-Val-d-Cit-PAB-PNP is a cleavable ADC linker that can be used for synthesizing antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.80%
- CAS No.: 1350456-68-6
- Formula: C35H43N7O11
- Molecular Weight:737.76
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 1350456-68-6
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Appearance Solid
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Molecular Weight 737.76
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Formula C35H43N7O11
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Color White to off-white
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SMILES
O=C(OCC1=CC=C(NC([C@H](NC([C@H](NC(CCCCCN2C(C=CC2=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)OC3=CC=C([N+]([O-])=O)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (67.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3555 mL | 6.7773 mL | 13.5545 mL | 33.8864 mL |
| 5 mM | 0.2711 mL | 1.3555 mL | 2.7109 mL | 6.7773 mL | |
| 10 mM | 0.1355 mL | 0.6777 mL | 1.3555 mL | 3.3886 mL | |
| 15 mM | 0.0904 mL | 0.4518 mL | 0.9036 mL | 2.2591 mL | |
| 20 mM | 0.0678 mL | 0.3389 mL | 0.6777 mL | 1.6943 mL | |
| 25 mM | 0.0542 mL | 0.2711 mL | 0.5422 mL | 1.3555 mL | |
| 30 mM | 0.0452 mL | 0.2259 mL | 0.4518 mL | 1.1295 mL | |
| 40 mM | 0.0339 mL | 0.1694 mL | 0.3389 mL | 0.8472 mL | |
| 50 mM | 0.0271 mL | 0.1355 mL | 0.2711 mL | 0.6777 mL | |
| 60 mM | 0.0226 mL | 0.1130 mL | 0.2259 mL | 0.5648 mL |