2. Antibody-drug Conjugate/ADC Related Metabolic Enzyme/Protease
  3. Drug-Linker Conjugates for ADC NAMPT
  4. L2-FK866

L2-FK866 is an ADC payload-linker conjugate (Drug-linker conjugate for ADC). L2-FK866 contains the ADC linker (Val-Cit-p-aminobenzyl) and the NAMPT inhibitor FK866 (HY-50876). L2-FK866 can be conjugated with Dinutuximab (HY-P9933) to form an ADC. L2-FK866 is applicable to neuroblastoma research.

For research use only. We do not sell to patients.

L2-FK866

L2-FK866 Chemical Structure

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L2-FK866 Related Antibodies

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Description

L2-FK866 is an ADC payload-linker conjugate (Drug-linker conjugate for ADC). L2-FK866 contains the ADC linker (Val-Cit-p-aminobenzyl) and the NAMPT inhibitor FK866 (HY-50876). L2-FK866 can be conjugated with Dinutuximab (HY-P9933) to form an ADC. L2-FK866 is applicable to neuroblastoma research[1].

Molecular Weight

1388.61

Formula

C64H89N15O16S2
SMILES

O=C(C1=CC(NC(OCC2=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCN3N=NC(CNC([C@H]4N(S(=O)(C=C)=O)CCN(S(=O)(C=C)=O)C4)=O)=C3)=O)=O)=O)C=C2)=O)=CC=C1)N5CCC(CCCCNC(/C=C/C6=CC=CN=C6)=O)CC5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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L2-FK866 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L2-FK866Drug-Linker Conjugates for ADCNAMPTNicotinamide phosphoribosyl transferasePBEFVisfatinpre-B cell-enhancing factorPre-B cell colony enhancing factorAMPK pathwayneuroblastoma cellsxenograft mouse modelsNAD+ATPNAD+ salvage pathwayapoptosisIMR-32GD2Inhibitorinhibitorinhibit

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