MC-VC-PAB-Tubulysin M
Based on 1 Customer Validation
MC-vc-PAB-Tubulysin M is a Drug-Linker Conjugates for ADC, consisting of a microtubule polymerization inhibitor Tubulysin M (an ADC cytotoxin) (HY-N7053) and MC-vc-PAB (a cleavable ADC linker).
For research use only. We do not sell to patients.
- Purity: 98.26%
- CAS No.: 1639939-56-2
- Formula: C66H93N11O15S
- Molecular Weight:1312.57
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
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Auristatin |
MC-vc-PAB-Tubulysin is composed of a microtubule polymerization inhibitor Tubulysin M (an ADC cytotoxin) (HY-N7053) and MC-vc-PAB (a cleavable ADC linker), and is used to synthesize ADCs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1639939-56-2
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Appearance Solid
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Molecular Weight 1312.57
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Formula C66H93N11O15S
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Color White to off-white
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SMILES
CC(O[C@@H](C1=NC(C(N[C@H](C[C@H](C)C(O)=O)CC2=CC=CC=C2)=O)=CS1)C[C@H](C(C)C)N(C)C([C@H]([C@@H](C)CC)NC([C@@H](CCCC3)N3C(OCC(C=C4)=CC=C4NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN(C5=O)C(C=C5)=O)=O)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (38.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7619 mL | 3.8093 mL | 7.6186 mL | 19.0466 mL |
| 5 mM | 0.1524 mL | 0.7619 mL | 1.5237 mL | 3.8093 mL | |
| 10 mM | 0.0762 mL | 0.3809 mL | 0.7619 mL | 1.9047 mL | |
| 15 mM | 0.0508 mL | 0.2540 mL | 0.5079 mL | 1.2698 mL | |
| 20 mM | 0.0381 mL | 0.1905 mL | 0.3809 mL | 0.9523 mL | |
| 25 mM | 0.0305 mL | 0.1524 mL | 0.3047 mL | 0.7619 mL | |
| 30 mM | 0.0254 mL | 0.1270 mL | 0.2540 mL | 0.6349 mL |
MC-VC-PAB-Tubulysin M Related Classifications
HY-136313 Related Classifications
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