1. Cell Cycle/DNA Damage
    Cytoskeleton
    Apoptosis
  2. Microtubule/Tubulin
    Apoptosis
  3. Tubulysin M

Tubulysin M 

Cat. No.: HY-N7053
Handling Instructions

Tubulysin M is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin M is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.

For research use only. We do not sell to patients.

Tubulysin M Chemical Structure

Tubulysin M Chemical Structure

CAS No. : 936691-46-2

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Description

Tubulysin M is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis[1]. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range[2]. Tubulysin M is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[3].

Molecular Weight

727.95

Formula

C₃₈H₅₇N₅O₇S

CAS No.

936691-46-2

SMILES

O=C(N[[email protected]@H]([[email protected]@H](C)CC)C(N(C)[[email protected]@H](C(C)C)C[[email protected]@H](OC(C)=O)C1=NC(C(N[[email protected]@H](CC2=CC=CC=C2)C[[email protected]](C)C(O)=O)=O)=CS1)=O)[[email protected]@H]3N(C)CCCC3

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Keywords:

Tubulysin MMicrotubule/TubulinApoptosisInhibitorinhibitorinhibit

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