Aminoethyl-SS-propionic acid
Based on 1 Customer Validation
Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- CAS No.: 15579-00-7
- Formula: C5H11NO2S2
- Molecular Weight:181.28
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Disulfide Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15579-00-7
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Appearance Solid
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Molecular Weight 181.28
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Formula C5H11NO2S2
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Color White to off-white
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SMILES
O=C(O)CCSSCCN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 125 mg/mL (689.54 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 11.11 mg/mL (61.29 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 5.5163 mL | 27.5816 mL | 55.1633 mL | 137.9082 mL |
| 5 mM | 1.1033 mL | 5.5163 mL | 11.0327 mL | 27.5816 mL | |
| 10 mM | 0.5516 mL | 2.7582 mL | 5.5163 mL | 13.7908 mL | |
| 15 mM | 0.3678 mL | 1.8388 mL | 3.6776 mL | 9.1939 mL | |
| 20 mM | 0.2758 mL | 1.3791 mL | 2.7582 mL | 6.8954 mL | |
| 25 mM | 0.2207 mL | 1.1033 mL | 2.2065 mL | 5.5163 mL | |
| 30 mM | 0.1839 mL | 0.9194 mL | 1.8388 mL | 4.5969 mL | |
| 40 mM | 0.1379 mL | 0.6895 mL | 1.3791 mL | 3.4477 mL | |
| 50 mM | 0.1103 mL | 0.5516 mL | 1.1033 mL | 2.7582 mL | |
| 60 mM | 0.0919 mL | 0.4597 mL | 0.9194 mL | 2.2985 mL | |
| 80 mM | 0.0690 mL | 0.3448 mL | 0.6895 mL | 1.7239 mL | |
| 100 mM | 0.0552 mL | 0.2758 mL | 0.5516 mL | 1.3791 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Aminoethyl-SS-propionic acid Related Classifications
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