1. Antibody-drug Conjugate/ADC Related
    Cytoskeleton
    Cell Cycle/DNA Damage
  2. Drug-Linker Conjugates for ADC
    Microtubule/Tubulin
  3. Vat-Cit-PAB-Monomethyl Dolastatin 10

Vat-Cit-PAB-Monomethyl Dolastatin 10 

Cat. No.: HY-126492
Handling Instructions

Vat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.

For research use only. We do not sell to patients.

Vat-Cit-PAB-Monomethyl Dolastatin 10 Chemical Structure

Vat-Cit-PAB-Monomethyl Dolastatin 10 Chemical Structure

CAS No. : 1415329-13-3

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Description

Vat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.

IC50 & Target[1]

Auristatin

 

Molecular Weight

1176.51

Formula

C₆₀H₉₃N₁₁O₁₁S

CAS No.

1415329-13-3

SMILES

CC(C)[[email protected]](N)C(N[[email protected]@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[[email protected]@H](C(C)C)C(N[[email protected]@H](C(C)C)C(N(C)[[email protected]@H]([[email protected]@H](C)CC)[[email protected]](OC)CC(N2CCC[[email protected]@H]2[[email protected]](OC)[[email protected]@H](C)C(N[[email protected]](C3=NC=CS3)CC4=CC=CC=C4)=O)=O)=O)=O)=O)C=C1)=O)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Vat-Cit-PAB-Monomethyl Dolastatin 10Drug-Linker Conjugates for ADCMicrotubule/TubulinInhibitorinhibitorinhibit

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Vat-Cit-PAB-Monomethyl Dolastatin 10
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