1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. Vat-Cit-PAB-Monomethyl Dolastatin 10

Vat-Cit-PAB-Monomethyl Dolastatin 10 is a agent-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.

For research use only. We do not sell to patients.

Vat-Cit-PAB-Monomethyl Dolastatin 10 Chemical Structure

Vat-Cit-PAB-Monomethyl Dolastatin 10 Chemical Structure

CAS No. : 1415329-13-3

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Description

Vat-Cit-PAB-Monomethyl Dolastatin 10 is a agent-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.

IC50 & Target[1]

Auristatin

 

Molecular Weight

1176.51

Formula

C60H93N11O11S

CAS No.
SMILES

CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N2CCC[C@@H]2[C@H](OC)[C@@H](C)C(N[C@H](C3=NC=CS3)CC4=CC=CC=C4)=O)=O)=O)=O)=O)C=C1)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Vat-Cit-PAB-Monomethyl Dolastatin 10 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Vat-Cit-PAB-Monomethyl Dolastatin 10
Cat. No.:
HY-126492
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