1415329-13-3
Chemical Structure
Vat-Cit-PAB-Monomethyl Dolastatin 10
- CAS No.: 1415329-13-3
- Formula:C60H93N11O11S
- Molecular Weight:1176.51
IUPAC Name: 4-((S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanamido)benzyl ((S)-1-(((S)-1-(((3R,4S,5S)-3-methoxy-1-((R)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)(methyl)am
InChIKey: GXCUHADNABTLIA-DBHCVZOLSA-N
SMILES: CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N2CCC[C@@H]2[C@H](OC)[C@@H](C)C(N[C@H](C3=NC=CS3)CC4=CC=CC=C4)=O)=O)=O)=O)=O)C=C1)=O)=O
Biological Activity: Vat-Cit-PAB-Monomethyl Dolastatin 10 is a agent-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.
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Vat-Cit-PAB-Monomethyl Dolastatin 10 | Vat-Cit-PAB-Monomethyl Dolastatin 10 is a agent-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB. | |||||||||||||||||||||
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Keywords
