1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. DM4-SMCC

DM4-SMCC 

Cat. No.: HY-126494
Handling Instructions

DM4-SMCC is a drug-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker.

For research use only. We do not sell to patients.

DM4-SMCC Chemical Structure

DM4-SMCC Chemical Structure

CAS No. : 1228105-52-9

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Description

DM4-SMCC is a drug-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker[1].

IC50 & Target[1]

Maytansinoids

 

Molecular Weight

1114.69

Formula

C₅₄H₇₂ClN₅O₁₆S

CAS No.

1228105-52-9

SMILES

C[[email protected]]12[[email protected]]([[email protected]@H]([[email protected]](O3)([H])C[[email protected]]([[email protected]](/C=C/C=C(C)/CC4=CC(N(C)C(C[[email protected]]2([H])OC([[email protected]](C)N(C)C(CCC(C)(C)SC(C5)C(N(CC6CCC(C(ON7C(CCC7=O)=O)=O)CC6)C5=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

DM4-SMCCDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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