1228105-52-9
Chemical Structure
DM4-SMCC
- CAS No.: 1228105-52-9
- Formula:C54H72ClN5O16S
- Molecular Weight:1114.69
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 4-((3-((5-(((S)-1-(((14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-2-methyl-5-oxopentan-2-yl)thio)-2,5-dioxopyrrolidin-1-yl)methyl)cyclohexane-1-carboxylate
InChIKey: VYNFFBGYRBMGDS-NPCPMBKGSA-N
SMILES: C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCC(C)(C)SC(C5)C(N(CC6CCC(C(ON7C(CCC7=O)=O)=O)CC6)C5=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Biological Activity: DM4-SMCC is a agent-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DM4-SMCC | 96.86% | DM4-SMCC is a agent-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker. | ||||||||||||||||||||
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Keywords
