Mal-PEG8-Val-Cit-PAB-PNP
Based on 1 Customer Validation
Mal-PEG8-Val-Cit-PAB-PNP is a ADC linker. Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
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- Pureté : 96.28%
- Formule: C48H69N7O19
- Masse moléculaire:1048.10
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
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Activité biologique
Description
In Vitro
Mal-PEG8-Val-Cit-PAB-PNP contains multiple functional domains including Mal, PEG8, Val-Cit, PAB, and PNP, and has functions such as thiol coupling, water solubility enhancement, enzymatic cleavage, and amide bond coupling of drug molecules.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Masse moléculaire 1048.10
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Formule C48H69N7O19
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Color White to off-white
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SMILES
O=C(C=CC1=O)N1CCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(OC3=CC=C([N+]([O-])=O)C=C3)=O)C=C2)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (95.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (238 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9541 mL | 4.7705 mL | 9.5411 mL | 23.8527 mL |
| 5 mM | 0.1908 mL | 0.9541 mL | 1.9082 mL | 4.7705 mL | |
| 10 mM | 0.0954 mL | 0.4771 mL | 0.9541 mL | 2.3853 mL | |
| 15 mM | 0.0636 mL | 0.3180 mL | 0.6361 mL | 1.5902 mL | |
| 20 mM | 0.0477 mL | 0.2385 mL | 0.4771 mL | 1.1926 mL | |
| 25 mM | 0.0382 mL | 0.1908 mL | 0.3816 mL | 0.9541 mL | |
| 30 mM | 0.0318 mL | 0.1590 mL | 0.3180 mL | 0.7951 mL | |
| 40 mM | 0.0239 mL | 0.1193 mL | 0.2385 mL | 0.5963 mL | |
| 50 mM | 0.0191 mL | 0.0954 mL | 0.1908 mL | 0.4771 mL | |
| 60 mM | 0.0159 mL | 0.0795 mL | 0.1590 mL | 0.3975 mL | |
| 80 mM | 0.0119 mL | 0.0596 mL | 0.1193 mL | 0.2982 mL |
Mal-PEG8-Val-Cit-PAB-PNP Related Classifications
HY-W591339 Related Classifications
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