Mal-PEG8-Val-Cit-PAB-PNP

Cat. No.: HY-W591339 Purity: 96.28%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Mal-PEG8-Val-Cit-PAB-PNP is a ADC linker. Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Mal-PEG8-Val-Cit-PAB-PNP Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
Customer Review

Description

Mal-PEG8-Val-Cit-PAB-PNP is a ADC linker. Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).

Molecular Weight

1048.10

Formula

C₄₈H₆₉N₇O₁₉

Appearance

Solid

Color

White to off-white

SMILES

O=C(C=CC1=O)N1CCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(OC3=CC=C([N+]([O-])=O)C=C3)=O)C=C2)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (95.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.9541 mL	4.7705 mL	9.5411 mL
5 mM	0.1908 mL	0.9541 mL	1.9082 mL
10 mM	0.0954 mL	0.4771 mL	0.9541 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.28%

Select Batch:

Data Sheet (238 KB) SDS (251 KB)

COA (242 KB) HNMR (324 KB) LCMS (104 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.9541 mL	4.7705 mL	9.5411 mL	23.8527 mL
	5 mM	0.1908 mL	0.9541 mL	1.9082 mL	4.7705 mL
	10 mM	0.0954 mL	0.4771 mL	0.9541 mL	2.3853 mL
	15 mM	0.0636 mL	0.3180 mL	0.6361 mL	1.5902 mL
	20 mM	0.0477 mL	0.2385 mL	0.4771 mL	1.1926 mL
	25 mM	0.0382 mL	0.1908 mL	0.3816 mL	0.9541 mL
	30 mM	0.0318 mL	0.1590 mL	0.3180 mL	0.7951 mL
	40 mM	0.0239 mL	0.1193 mL	0.2385 mL	0.5963 mL
	50 mM	0.0191 mL	0.0954 mL	0.1908 mL	0.4771 mL
	60 mM	0.0159 mL	0.0795 mL	0.1590 mL	0.3975 mL
	80 mM	0.0119 mL	0.0596 mL	0.1193 mL	0.2982 mL