1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. N-(Iodoacetamido)-Doxorubicin

N-(Iodoacetamido)-Doxorubicin 

Cat. No.: HY-141158
Handling Instructions

N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

N-(Iodoacetamido)-Doxorubicin Chemical Structure

N-(Iodoacetamido)-Doxorubicin Chemical Structure

CAS No. : 114390-30-6

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Description

N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

711.45

Formula

C₂₉H₃₀INO₁₂

CAS No.

114390-30-6

SMILES

COC1=CC=CC2=C1C(C3=C(C2=O)C(O)=C4C([[email protected]@H](O[[email protected]@H]5O[[email protected]@H](C)[[email protected]@H](O)[[email protected]@H](NC(CI)=O)C5)C[[email protected]@](C(CO)=O)(O)C4)=C3O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

N-(Iodoacetamido)-DoxorubicinADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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N-(Iodoacetamido)-Doxorubicin
Cat. No.:
HY-141158
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