Fmoc-Phe-Lys(Boc)-PAB-PNP
Based on 1 publication(s) in Google Scholar
Fmoc-Phe-Lys(Boc)-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.15%
- CAS No.: 1646299-50-4
- Formula: C49H51N5O11
- Molecular Weight:885.96
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Fmoc-Phe-Lys(Boc)-PAB-PNP
More
Biological Activity
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Protease Cleavable Linker |
Cleavable Linker |
Chemical Information
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CAS No. 1646299-50-4
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Appearance Solid
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Molecular Weight 885.96
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Formula C49H51N5O11
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Color White to off-white
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SMILES
O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCC(C=C2)=CC=C2NC([C@H](CCCCNC(OC(C)(C)C)=O)NC([C@H](CC3=CC=CC=C3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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CNS Neurosci Ther
G-alpha interacting protein interacting protein, C terminus 1 regulates epileptogenesis by increasing the expression of metabotropic glutamate receptor 7. [Abstract]2022 Jan;28(1):126-138. PMID: 34676980
Solvent & Solubility
DMSO : 6 mg/mL (6.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.1287 mL | 5.6436 mL | 11.2872 mL | 28.2180 mL |
| 5 mM | 0.2257 mL | 1.1287 mL | 2.2574 mL | 5.6436 mL |
Fmoc-Phe-Lys(Boc)-PAB-PNP Related Classifications
HY-114430 Related Classifications
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