1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Fmoc-Phe-Lys(Boc)-PAB-PNP

Fmoc-Phe-Lys(Boc)-PAB-PNP 

Cat. No.: HY-114430 Purity: 98.67% ee.: 99.73%
Handling Instructions

Fmoc-Phe-Lys(Boc)-PAB-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Fmoc-Phe-Lys(Boc)-PAB-PNP Chemical Structure

Fmoc-Phe-Lys(Boc)-PAB-PNP Chemical Structure

CAS No. : 1646299-50-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
50 mg USD 350 In-stock
Estimated Time of Arrival: December 31
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200 mg   Get quote  

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Description

Fmoc-Phe-Lys(Boc)-PAB-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

IC50 & Target

ADC linker

Molecular Weight

885.96

Formula

C₄₉H₅₁N₅O₁₁

CAS No.

1646299-50-4

SMILES

O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCC(C=C2)=CC=C2NC([[email protected]](CCCCNC(OC(C)(C)C)=O)NC([[email protected]](CC3=CC=CC=C3)NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 6 mg/mL (6.77 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1287 mL 5.6436 mL 11.2872 mL
5 mM 0.2257 mL 1.1287 mL 2.2574 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Fmoc-Phe-Lys(Boc)-PAB-PNP
Cat. No.:
HY-114430
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