MC-VC-PAB-NH2 TFA
Based on 1 Customer Validation
MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 1616727-21-9
- Formula: C33H47F3N8O10
- Molecular Weight:772.77
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1616727-21-9
-
Appearance Solid
-
Molecular Weight 772.77
-
Formula C33H47F3N8O10
-
Color White to off-white
-
SMILES
OC(C(F)(F)F)=O.NCCNC(OCC1=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)C=C1)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (129.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2940 mL | 6.4702 mL | 12.9405 mL | 32.3512 mL |
| 5 mM | 0.2588 mL | 1.2940 mL | 2.5881 mL | 6.4702 mL | |
| 10 mM | 0.1294 mL | 0.6470 mL | 1.2940 mL | 3.2351 mL | |
| 15 mM | 0.0863 mL | 0.4313 mL | 0.8627 mL | 2.1567 mL | |
| 20 mM | 0.0647 mL | 0.3235 mL | 0.6470 mL | 1.6176 mL | |
| 25 mM | 0.0518 mL | 0.2588 mL | 0.5176 mL | 1.2940 mL | |
| 30 mM | 0.0431 mL | 0.2157 mL | 0.4313 mL | 1.0784 mL | |
| 40 mM | 0.0324 mL | 0.1618 mL | 0.3235 mL | 0.8088 mL | |
| 50 mM | 0.0259 mL | 0.1294 mL | 0.2588 mL | 0.6470 mL | |
| 60 mM | 0.0216 mL | 0.1078 mL | 0.2157 mL | 0.5392 mL | |
| 80 mM | 0.0162 mL | 0.0809 mL | 0.1618 mL | 0.4044 mL | |
| 100 mM | 0.0129 mL | 0.0647 mL | 0.1294 mL | 0.3235 mL |
Powered by Bioz