1. Antibody-drug Conjugate/ADC Related
    PROTAC
  2. ADC Linker
    PROTAC Linker
  3. Propargyl-PEG3-acid

Propargyl-PEG3-acid 

Cat. No.: HY-126975
Handling Instructions

Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid.

For research use only. We do not sell to patients.

Propargyl-PEG3-acid Chemical Structure

Propargyl-PEG3-acid Chemical Structure

CAS No. : 1347760-82-0

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Description

Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid[1].

IC50 & Target

PEGs

 

Non-cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Molecular Weight

216.23

Formula

C₁₀H₁₆O₅

CAS No.

1347760-82-0

SMILES

O=C(O)CCOCCOCCOCC#C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Propargyl-PEG3-acidADC LinkerPROTAC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Propargyl-PEG3-acid
Cat. No.:
HY-126975
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