Fmoc-GGFG-DXd
Based on 1 Customer Validation
Fmoc-GGFG-DXd is a drug-linker conjugate for ADC. Fmoc-GGFG-DXd contains a ADC linker Fmoc-GGFG and a DNA topoisomerase I inhibitor DXd (HY-13631D).
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 1599440-11-5
- Formula: C57H55FN8O12
- Molecular Weight:1063.09
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
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Traditional Cytotoxic Agents |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1599440-11-5
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Appearance Solid
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Molecular Weight 1063.09
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Formula C57H55FN8O12
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Color Light yellow to yellow
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SMILES
O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)NCC(NCC(N[C@@H](CC4=CC=CC=C4)C(NCC(NCOCC(N[C@@H]5C6=C7C(C(N8C7)=CC([C@](O)(C(OC9)=O)CC)=C9C8=O)=NC%10=CC(F)=C(C)C(CC5)=C%106)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 175 mg/mL (164.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.9407 mL | 4.7033 mL | 9.4065 mL | 23.5164 mL |
| 5 mM | 0.1881 mL | 0.9407 mL | 1.8813 mL | 4.7033 mL | |
| 10 mM | 0.0941 mL | 0.4703 mL | 0.9407 mL | 2.3516 mL | |
| 15 mM | 0.0627 mL | 0.3136 mL | 0.6271 mL | 1.5678 mL | |
| 20 mM | 0.0470 mL | 0.2352 mL | 0.4703 mL | 1.1758 mL | |
| 25 mM | 0.0376 mL | 0.1881 mL | 0.3763 mL | 0.9407 mL | |
| 30 mM | 0.0314 mL | 0.1568 mL | 0.3136 mL | 0.7839 mL | |
| 40 mM | 0.0235 mL | 0.1176 mL | 0.2352 mL | 0.5879 mL | |
| 50 mM | 0.0188 mL | 0.0941 mL | 0.1881 mL | 0.4703 mL | |
| 60 mM | 0.0157 mL | 0.0784 mL | 0.1568 mL | 0.3919 mL | |
| 80 mM | 0.0118 mL | 0.0588 mL | 0.1176 mL | 0.2940 mL | |
| 100 mM | 0.0094 mL | 0.0470 mL | 0.0941 mL | 0.2352 mL |
Fmoc-GGFG-DXd Related Classifications
HY-156848 Related Classifications
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