Tetrazine-PEG7-amine hydrochloride
Based on 1 Customer Validation
Tetrazine-PEG7-amine hydrochloride is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetrazine-PEG7-amine (hydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
For research use only. We do not sell to patients.
- Purity: 98.56%
- Formula: C26H43ClN6O8
- Molecular Weight:603.11
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 603.11
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Formula C26H43ClN6O8
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Color Purple to purplish red
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SMILES
O=C(CCOCCOCCOCCOCCOCCOCCOCCN)NCC(C=C1)=CC=C1C2=NN=CN=N2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 200 mg/mL (331.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6581 mL | 8.2904 mL | 16.5807 mL | 41.4518 mL |
| 5 mM | 0.3316 mL | 1.6581 mL | 3.3161 mL | 8.2904 mL | |
| 10 mM | 0.1658 mL | 0.8290 mL | 1.6581 mL | 4.1452 mL | |
| 15 mM | 0.1105 mL | 0.5527 mL | 1.1054 mL | 2.7635 mL | |
| 20 mM | 0.0829 mL | 0.4145 mL | 0.8290 mL | 2.0726 mL | |
| 25 mM | 0.0663 mL | 0.3316 mL | 0.6632 mL | 1.6581 mL | |
| 30 mM | 0.0553 mL | 0.2763 mL | 0.5527 mL | 1.3817 mL | |
| 40 mM | 0.0415 mL | 0.2073 mL | 0.4145 mL | 1.0363 mL | |
| 50 mM | 0.0332 mL | 0.1658 mL | 0.3316 mL | 0.8290 mL | |
| 60 mM | 0.0276 mL | 0.1382 mL | 0.2763 mL | 0.6909 mL | |
| 80 mM | 0.0207 mL | 0.1036 mL | 0.2073 mL | 0.5181 mL | |
| 100 mM | 0.0166 mL | 0.0829 mL | 0.1658 mL | 0.4145 mL |
Tetrazine-PEG7-amine hydrochloride Related Classifications
HY-148211 Related Classifications
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