1. PROTAC
    Antibody-drug Conjugate/ADC Related
  2. PROTAC Linker
    ADC Linker
  3. Bis-PEG7-acid

Bis-PEG7-acid 

Cat. No.: HY-126892
Handling Instructions

Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Bis-PEG7-acid Chemical Structure

Bis-PEG7-acid Chemical Structure

CAS No. : 94376-75-7

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Description

Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

PEGs

 

Cleavable

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Molecular Weight

426.46

Formula

C₁₈H₃₄O₁₁

CAS No.

94376-75-7

SMILES

O=C(O)CCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Bis-PEG7-acidPROTAC LinkerADC LinkerAntibody-drug conjugates linkerPEGPROTAClinkerE3ubiquitinligaseproteincleavableADCantibody-drugconjugatesInhibitorinhibitorinhibit

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Bis-PEG7-acid
Cat. No.:
HY-126892
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