MCC-AAQ-Exa
Based on 1 Customer Validation
MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment.
For research use only. We do not sell to patients.
- Purity: 95.33%
- CAS No.: 3052836-65-1
- Formula: C47H53FN8O11
- Molecular Weight:924.97
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3052836-65-1
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Appearance Solid
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Molecular Weight 924.97
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Formula C47H53FN8O11
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Color Light yellow to yellow
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SMILES
O=C(C1CCC(CC1)CN2C(C=CC2=O)=O)N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (108.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0811 mL | 5.4056 mL | 10.8112 mL | 27.0279 mL |
| 5 mM | 0.2162 mL | 1.0811 mL | 2.1622 mL | 5.4056 mL | |
| 10 mM | 0.1081 mL | 0.5406 mL | 1.0811 mL | 2.7028 mL | |
| 15 mM | 0.0721 mL | 0.3604 mL | 0.7207 mL | 1.8019 mL | |
| 20 mM | 0.0541 mL | 0.2703 mL | 0.5406 mL | 1.3514 mL | |
| 25 mM | 0.0432 mL | 0.2162 mL | 0.4324 mL | 1.0811 mL | |
| 30 mM | 0.0360 mL | 0.1802 mL | 0.3604 mL | 0.9009 mL | |
| 40 mM | 0.0270 mL | 0.1351 mL | 0.2703 mL | 0.6757 mL | |
| 50 mM | 0.0216 mL | 0.1081 mL | 0.2162 mL | 0.5406 mL | |
| 60 mM | 0.0180 mL | 0.0901 mL | 0.1802 mL | 0.4505 mL | |
| 80 mM | 0.0135 mL | 0.0676 mL | 0.1351 mL | 0.3378 mL | |
| 100 mM | 0.0108 mL | 0.0541 mL | 0.1081 mL | 0.2703 mL |
MCC-AAQ-Exa Related Classifications
HY-174279 Related Classifications
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