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Results for "

Antibiotics Inhibitors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (499) 5-HT Receptor (2) Acyltransferase (1) ADC Cytotoxin (12) Adenosine Deaminase (1) Akt (3) Aminoacyl-tRNA Synthetase (4) Aminopeptidase (1) AMPK (3) Antifolate (10) AP-1 (2) Apoptosis (60) Arginase (1) Atg8/LC3 (1) ATP Synthase (4) Aurora Kinase (6) Autophagy (29) Bacterial (483) Bcl-2 Family (1) Beta-lactamase (23) Biochemical Assay Reagents (1) Btk (1) c-Myc (1) Calcium Channel (3) Carbonic Anhydrase (1) Caspase (6) CDK (1) CGRP Receptor (1) CRISPR/Cas9 (1) CRM1 (1) Cytochrome P450 (3) Dengue virus (1) Deubiquitinase (1) Dihydrofolate reductase (DHFR) (3) Dipeptidyl Peptidase (1) DNA Alkylator/Crosslinker (1) DNA Methyltransferase (1) DNA/RNA Synthesis (56) Dopamine Receptor (2) Drug Metabolite (2) Elastase (1) Endogenous Metabolite (16) Endothelin Receptor (1) Enolase (2) Farnesyl Transferase (2) Flavivirus (3) Fungal (49) GSK-3 (6) HBV (3) HCV (1) HIF/HIF Prolyl-Hydroxylase (3) Histamine Receptor (4) HIV (8) HIV Integrase (1) HIV Protease (1) HSP (6) HSV (9) Influenza Virus (7) Isotope-Labeled Compounds (20) JNK (3) MDM-2/p53 (3) Microtubule/Tubulin (2) Mitochondrial Metabolism (10) Mitophagy (5) MMP (6) Molecular Glues (1) Myosin (1) Na+/H+ Exchanger (NHE) (3) Na+/K+ ATPase (1) Necroptosis (2) NF-κB (4) Nucleoside Antimetabolite/Analog (1) Orthopoxvirus (12) Oxidative Phosphorylation (6) P-glycoprotein (1) Parasite (57) PDI (3) Penicillin-binding protein (PBP) (16) Phosphatase (1) Phospholipase (3) Photosystem II (1) PI3K (2) PKC (1) Potassium Channel (4) Proteasome (3) Proton Pump (4) Pyruvate Kinase (1) Ras (2) Reactive Oxygen Species (19) Reverse Transcriptase (1) SARS-CoV (3) Small Interfering RNA (siRNA) (2) STAT (3) TAM Receptor (1) TGF-beta/Smad (1) TGF-β Receptor (2) TNF Receptor (1) Topoisomerase (59) Tyrosinase (2) Wnt (6) β-catenin (6)
By Research Areas:	Cancer (191) Cardiovascular Disease (9) Endocrinology (1) Infection (548) Inflammation/Immunology (51) Metabolic Disease (11) Neurological Disease (15)
Oligonucleotides:	siRNAs (2)

598

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

MCE Kits

196

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1327

Chlortetracycline hydrochloride 3 Publications Verification 7-Chlorotetracycline hydrochloride	Bacterial Antibiotic Parasite	Infection Inflammation/Immunology
Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a *antibiotic* that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore *antibiotic, inhibiting* binding of aminoacyl-tRNA to ribosomes .

HY-N1724

Concanamycin A 5+ Cited Publications Antibiotic X 4357B; Folimycin; X 4357B	Proton Pump Bacterial Antibiotic	Infection Inflammation/Immunology Cancer
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide *antibiotic, a vacuolar type H ⁺-ATPase (V-ATPase)* inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research ^- .

HY-113753

PDF-IN-1	Antibiotic	Infection
PDF-IN-1 (compound 2) is a potential Peptide deformylase (PDF) inhibitor. PDF-IN-1 can be used for the development of new broad-spectrum antibiotics 。

HY-P5459

Elafin(human)	Bacterial Elastase	Infection
Elafin,also known as elafin-specific inhibitor (ESI) or skin anti-leucoprotease (SKALP), is a low molecular weight inhibitor of human neutrophil elastase (HNE) and proteinase 3 in lung. Elafin is *antibiotic* against Pseudomonas aeruginosa and Staphylococcus aureus .

HY-113542

Blasticidin A (+)-Blasticidin A	Bacterial Antibiotic Parasite	Infection
Blasticidin A ((+)-Blasticidin A) is an inhibitor of Aflatoxin production by Aspergillus parasiticus. Blasticidin A almost completely inhibits Aflatoxin production at 0.5 μM . Blasticidin A is a potent antibiotic produced by Streptomyces, inhibits Aflatoxin production without strong growth inhibition toward Aflatoxin-producing fungi .

HY-158820

Cosdosiran QPI-1007	Small Interfering RNA (siRNA) Caspase	Cardiovascular Disease
Cosdosiran is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?

HY-158820A

Cosdosiran sodium QPI-1007 sodium	Small Interfering RNA (siRNA) Caspase	Cardiovascular Disease
Cosdosiran sodium is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?

HY-E70364

IgdE protease	Biochemical Assay Reagents	Inflammation/Immunology
IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .

HY-B1327A

Chlortetracycline 7-Chlorotetracycline	Bacterial Antibiotic Parasite	Infection Inflammation/Immunology
Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a *antibiotic* that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore *antibiotic, inhibiting* binding of aminoacyl-tRNA to ribosomes .

HY-B1327R

Chlortetracycline hydrochloride (Standard)	Bacterial Antibiotic Parasite	Infection Inflammation/Immunology
Chlortetracycline (hydrochloride) (Standard) is the analytical standard of Chlortetracycline (hydrochloride). This product is intended for research and analytical applications. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic that inhibits the binding of aminoacyl-tRNA to ribosomes.

HY-15739

Ansamitocin P-3 5+ Cited Publications Antibiotic C 15003P3; Maytansinol isobutyrate	Microtubule/Tubulin ADC Cytotoxin Bacterial Antibiotic	Infection Cancer
Ansamitocin P-3 (Antibiotic C 15003P3) is a microtubule inhibitor. Ansamitocin P-3 is a macrocyclic antitumor antibiotic.

HY-120383

Amicetin Sacromycin; U-4761	Antibiotic Bacterial	Infection
Amicetin is a potent antibiotic. Amicetin shows antibiotic activities against gram-positive bacteria. Amicetin inhibits protein synthesis .

HY-P3884

Arylomycin A2	Bacterial Antibiotic	Infection
Arylomycin A2, an *antibiotic* (Antibiotic), is a lipopeptide type I signal peptidase (SPase I) inhibitor. Arylomycin A2 has antibacterial effects .

HY-107767

Antibiotic DC 81 DC 81	Antibiotic Apoptosis DNA/RNA Synthesis	Cancer
Antibiotic DC 81 (DC 81), an antitumor antibiotic produced by Streptomyces species, is a PBD (pyrrolo[2,1-c][1,4]benzodiazepine). Antibiotic DC 81 is potent inhibitor of nucleic acid synthesis. Antibiotic DC 81 can recognize and bind to specific sequences of DNA and form a labile covalent adduct .

HY-B1434

7-Aminocephalosporanic acid 1 Publications Verification 7-ACA	Beta-lactamase Bacterial Antibiotic	Infection
7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an *antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics* and an effective β-lactamase inhibitor .

HY-B0472

Streptomycin sulfate

15+ Cited Publications

Bacterial Antibiotic Infection

Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
HY-B1781A

Sulfachloropyridazine sodium

Sulfachlorpyridazine sodium
Bacterial Antibiotic Infection

Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits bacterial growth .

Streptomycin sulfate 15+ Cited Publications	Bacterial Antibiotic	Infection
Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

Sulfachloropyridazine sodium Sulfachlorpyridazine sodium	Bacterial Antibiotic	Infection
Sulfachloropyridazine (sodium) is a sulfonamide antibiotic that inhibits bacterial growth .

HY-157987

MBX3135	Bacterial	Infection
MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics .

HY-125552

Chlorothricin

Antibiotic Infection Inflammation/Immunology

Chlorothricin, an antibiotic, is an Inhibitor of porcine-heart malate dehydrogenases .
HY-119764

Ikarugamycin

2 Publications Verification

Antibiotic Others

Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) .
HY-N6665A

Cefquinome

Antibiotic Bacterial Infection

Cefquinome is a cephem antibiotic, which inhibits members of the Enterobacteriaceae .

Chlorothricin	Antibiotic	Infection Inflammation/Immunology
Chlorothricin, an antibiotic, is an Inhibitor of porcine-heart malate dehydrogenases .

Ikarugamycin 2 Publications Verification	Antibiotic	Others
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) .

Cefquinome	Antibiotic Bacterial	Infection
Cefquinome is a cephem *antibiotic, which inhibits* members of the Enterobacteriaceae .

HY-B1743

Puromycin CL13900	Bacterial Antibiotic Parasite	Infection
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743A

Puromycin dihydrochloride 175+ Cited Publications CL13900 dihydrochloride	Bacterial Antibiotic Parasite	Infection
Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-N6665

Cefquinome sulfate

Bacterial Antibiotic Infection

Cefquinome sulfate is a cephem antibiotic, which inhibits members of the Enterobacteriaceae .

Cefquinome sulfate	Bacterial Antibiotic	Infection
Cefquinome sulfate is a cephem *antibiotic, which inhibits* members of the Enterobacteriaceae .

HY-122350

Dactimicin sulfate SF-2052 sulfate	Antibiotic	Infection
Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .

HY-N6737

Aureothricin	Bacterial Antibiotic	Infection
Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin .

HY-112665

Virginiamycin Complex Streptogramin; Mikamycin; RP 7293	Antibiotic Bacterial	Infection
Virginiamycin complex contains two streptogramin antibiotics, virginiamycin M1 and virginiamycin S1 produced by S. virginiae. As a complex, the two antibiotics act synergistically to irreversibly inhibit protein synthesis in bacteria .

HY-B1300

Cefonicid sodium

Bacterial Antibiotic Infection

Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall.
HY-A0256A

Clavulanate potassium

Beta-lactamase Bacterial Antibiotic Infection

Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic .

Cefonicid sodium	Bacterial Antibiotic	Infection
Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall.

Clavulanate potassium	Beta-lactamase Bacterial Antibiotic	Infection
Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic .

HY-N10495

Seconeolitsine	Antibiotic Bacterial Topoisomerase	Infection
Seconeolitsine, an antibiotic, and is an inhibitor of targeting topoisomerase I (TopA). Seconeolitsine also is a new antimicrobial agent that can inhibit S. pneumoniae growth. Seconeolitsine can inhibit TopA relaxation activity with an IC₅₀ value of 17 μM. Seconeolitsine can be used for the research of S. pneumoniae infections resistant to other antibiotics .

HY-B0974

Methicillin sodium salt 4 Publications Verification Meticillin sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .

HY-P2047

Lavendomycin

Antibiotic FR-900201
Antibiotic Bacterial Infection

Lavendomycin is a peptide antibiotic from Streptomyces. Lavendomycin inhibits Gram-positive bacteria .

Lavendomycin Antibiotic FR-900201	Antibiotic Bacterial	Infection
Lavendomycin is a peptide antibiotic from Streptomyces. Lavendomycin inhibits Gram-positive bacteria .

HY-100496

Nucleocidin 4'-Fluoro-5'-O-sulfamoyladenosine; NSC 521007	Bacterial	Infection
Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein.

HY-W008923

Doxycycline monohydrate 75+ Cited Publications	MMP Bacterial Parasite Antibiotic	Infection Cancer
Doxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor .

HY-A0256B

Clavulanate lithium

5 Publications Verification

Beta-lactamase Bacterial Antibiotic Infection

Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic .
HY-119759

Lipoxamycin

Fungal Infection

Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

Clavulanate lithium 5 Publications Verification	Beta-lactamase Bacterial Antibiotic	Infection
Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic .

Lipoxamycin	Fungal	Infection
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

HY-P2020

Berninamycin A	Bacterial	Infection
Berninamycin A is a cyclic thiopeptide antibiotic first isolated from S. bernensis. It inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits. Cyclic thiopeptide antibiotics, including berninamycin A, induce the transcriptional activator TipA in Streptomyces.

HY-B1329

Apramycin sulfate 3 Publications Verification Nebramycin II sulfate	Bacterial Antibiotic	Infection
Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside *antibiotic* which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .

HY-B0408A

Clindamycin hydrochloride 5+ Cited Publications	Bacterial Antibiotic	Infection Cancer
Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.

HY-112639

Aristeromycin

Bacterial Infection Cancer

Aristeromycin, an adenosine analog, is an antibiotic and a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor .
HY-119759A

Lipoxamycin hemisulfate

Fungal Infection

Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

Aristeromycin	Bacterial	Infection Cancer
Aristeromycin, an adenosine analog, is an antibiotic and a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor .

Lipoxamycin hemisulfate	Fungal	Infection
Lipoxamycin hemisulfate is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

HY-17565A

Bleomycin hydrochloride 85+ Cited Publications	DNA/RNA Synthesis Antibiotic	Cancer
Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic .

HY-136461

Polyoxin D

Polyoxorim
Fungal Antibiotic Infection

Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor .
HY-N7115

Sultamicillin

Bacterial Antibiotic Infection

Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .

Polyoxin D Polyoxorim	Fungal Antibiotic	Infection
Polyoxin D (Polyoxorim), a polyoxin antibiotic fungicide, is a potent chitin synthetase inhibitor .

Sultamicillin	Bacterial Antibiotic	Infection
Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an *antibiotic* with antibacterial activity .

HY-N7111

Sultamicillin tosylate Sultamicillin (tosilate)	Bacterial Antibiotic	Infection
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an *antibiotic* with antibacterial activity .

HY-126406

Tirandamycin A	Bacterial DNA/RNA Synthesis Parasite Antibiotic	Infection
Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties .

HY-N11422

Mycaminosyltylonolide	Antibiotic Bacterial	Infection
Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis .

HY-10394

Linezolid 25+ Cited Publications PNU-100766	Bacterial Antibiotic	Infection
Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics .

HY-117778

SF2312	Enolase Bacterial Antibiotic	Infection Cancer
SF2312, a natural phosphonate *antibiotic* (Antibiotic), is a highly potent Enolase inhibitor with IC₅₀s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions .

HY-17025

Rifabutin 4 Publications Verification Ansamycin; LM-427	Bacterial Antibiotic	Infection
Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

Cat. No.	Product Name

HY-L067

Antibiotics Library

682 compounds

Antibiotics are types of antimicrobial products used for the treatment and prevention of bacterial infections. Antibiotics can kill or inhibit bacterial growth. Although the target of an antibiotic is bacteria, some antibiotics also attack fungi and protozoans. However, antibiotics rarely have an effect on viruses. The major mechanism underlying antibiotics is the inhibition or regulation of enzymes involved in cell wall biosynthesis, nucleic acid metabolism and repair, protein synthesis, or disruption of membrane structure. Many of these cellular functions targeted by antibiotics are most active in multiplying cells. Since there is often overlap in these functions between prokaryotic bacterial cells and eukaryotic mammalian cells, it is not surprising that some antibiotics have also been found to be useful as anticancer agents.

MCE supplies a unique collection of 682 antibiotics, including penicillins, cephalosporins, tetracyclines, macrolides, etc. MCE Antibiotics Library is a useful tool for anti-bacterial or anti-cancer drugs discovery.

HY-L112

Chemotherapy Drug Library

101 compounds

Chemotherapy is one of the most common treatments for cancer. It can be used alone for some types of cancer or in combination with other treatments such as radiation or surgery. Chemotherapy drugs usually target cells at different phases of the cell cycle and inhibit tumor proliferation and avoid cancer cell invasion and metastasis. It is a cancer treatment method that kills cancer cells with drugs.

Chemotherapeutic agents can be classified into alkylating agents, antimetabolites, antimicrotubular agents, antibiotics, etc. according to the mechanism of action. MCE offers a unique collection of 101 chemotherapy drugs, which is a useful tool for cancer treatment research.

HY-L084

Microbial Metabolite Library

1,109 compounds

Nature has been a source of medicinal products for millennia, with many useful active substances developed from plant sources. In the 20th century, the discovery of the penicillin was the starting point for drug discovery from microbial sources. Microorganisms， which have been considered to be a rich source of unique bioactive compounds, play an important role in the development of the chemistry of natural products and medical therapy. Microbial metabolites have proved to be affective antimicrobial agents, anti-tumor agents, enzyme inhibitors, anti-inflammatory agents, etc. Today, many microbial-originated antibiotics are available in the mark, and a large number of bioactive metabolites are used in medicine.

MCE provides a unique collection of 1,109 microbial metabolites, which is an important source of lead compounds and can be used for drug discovery.