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  4. Amoxicillin trihydrate mixture with potassium clavulanate (4:1)

Amoxicillin trihydrate mixture with potassium clavulanate (4:1) 

Cat. No.: HY-131165
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Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.

For research use only. We do not sell to patients.

Amoxicillin trihydrate mixture with potassium clavulanate (4:1) Chemical Structure

Amoxicillin trihydrate mixture with potassium clavulanate (4:1) Chemical Structure

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Description

Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3].

In Vitro

Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (1-100 µM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo

Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less[2].
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female ICR/Swiss mice[2]
Dosage: 7 mg/kg
Administration: Subcutaneous injection; every 8 h, for 24 hours
Result: Inhibited bacterial numbers in a dose-dependent manner.
Animal Model: Female ICR/Swiss mice[2]
Dosage: 7 mg/kg
Administration: Subcutaneous injection; every 8 h, for 4 days
Result: Survived all animals that were infected with organisms for which MICs were 1 mg/L or less, and with the two strains for which MICs were 2 mg/L, 20 to 40% mortality.
Animal Model: Swiss albino mice[3]
Dosage: 1.6 and 9.5 mg/kg
Administration: Oral administration; daily, for 7 or 14 days
Result: Improved the activity of Chlamydia trachomatis infection in mice.
Clinical Trial
Molecular Weight

656.70

Formula

C24H33KN4O13S
SMILES

OC([[email protected]@H]1N(C2=O)[[email protected]]([[email protected]@H]2NC([[email protected]@H](C3=CC=C(O)C=C3)N)=O)([H])SC1(C)C)=O.O=C([[email protected]@H](/C(O[[email protected]]4([H])C5)=C/CO)N4C5=O)O[K].[4].[3H2O]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

Amoxicillin trihydrate mixture with potassium clavulanate (4:1)AntibioticBacterialantibioticpolypeptidescell wallantimicrobialInhibitorinhibitorinhibit

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