2. Anti-infection
  3. Bacterial Antibiotic
  4. Amoxicillin

Amoxicillin  (Synonyms: Amoxycillin)

Cat. No.: HY-B0467A Purity: ≥98.0%
COA Handling Instructions

Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.

For research use only. We do not sell to patients.

Amoxicillin Chemical Structure

Amoxicillin Chemical Structure

CAS No. : 26787-78-0

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10 mM * 1 mL in DMSO USD 55 In-stock
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Based on 11 publication(s) in Google Scholar

Other Forms of Amoxicillin:

Amoxicillin Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3].

In Vitro

Amoxicillin (Amoxycillin) (1-100 µM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Amoxicillin Related Antibodies
In Vivo

Amoxicillin (Amoxycillin) (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less[2].
Amoxicillin (Amoxycillin) (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female ICR/Swiss mice[2]
Dosage: 7 mg/kg
Administration: Subcutaneous injection; every 8 h, for 24 hours
Result: Inhibited bacterial numbers in a dose-dependent manner.
Animal Model: Female ICR/Swiss mice[2]
Dosage: 7 mg/kg
Administration: Subcutaneous injection; every 8 h, for 4 days
Result: Survived all animals that were infected with organisms for which MICs were 1 mg/L or less, and with the two strains for which MICs were 2 mg/L, 20 to 40% mortality.
Animal Model: Swiss albino mice[3]
Dosage: 1.6 and 9.5 mg/kg
Administration: Oral administration; daily, for 7 or 14 days
Result: Improved the activity of Chlamydia trachomatis infection in mice.
Clinical Trial
Molecular Weight

365.40

Appearance

Solid

Formula

C16H19N3O5S
CAS No.
SMILES

OC([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=C(O)C=C3)N)=O)([H])SC1(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (228.05 mM; Need ultrasonic)

H2O : 2 mg/mL (5.47 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7367 mL 13.6836 mL 27.3673 mL
5 mM 0.5473 mL 2.7367 mL 5.4735 mL
10 mM 0.2737 mL 1.3684 mL 2.7367 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥98.0%

COA (247 KB) HNMR (210 KB)

Handling Instructions (2659 KB)
References
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Amoxicillin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Amoxicillin26787-78-0AmoxycillinBacterialAntibioticantibioticpolypeptidescell wallantimicrobialInhibitorinhibitorinhibit

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