2. Anti-infection
  3. Antibiotic
  4. Bleomycin A2

Bleomycin A2, an antitumor antibiotic promoting DNA-degradation, is an aspartate/asparagine-β-hydroxylase (AspH) inhibitor with an IC50 of 1.47 μM.

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Bleomycin A2

Bleomycin A2 Chemical Structure

CAS No. : 41432-97-7

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Based on 1 publication(s) in Google Scholar

Bleomycin A2 Related Antibodies

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Description

Bleomycin A2, an antitumor antibiotic promoting DNA-degradation, is an aspartate/asparagine-β-hydroxylase (AspH) inhibitor with an IC50 of 1.47 μM[1].

IC50 & Target

Glycopeptide

 

Molecular Weight

1512.62

Formula

C55H85N17O25S4
CAS No.
SMILES

O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@]([C@H](O)C)([H])C(NCCC2=NC(C3=NC(C(NCCC[S+](C)C)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@]6([H])[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O.O=S([O-])(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (66.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6611 mL 3.3055 mL 6.6110 mL
5 mM 0.1322 mL 0.6611 mL 1.3222 mL
View the Complete Stock Solution Preparation Table

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6611 mL 3.3055 mL 6.6110 mL 16.5276 mL
5 mM 0.1322 mL 0.6611 mL 1.3222 mL 3.3055 mL
10 mM 0.0661 mL 0.3306 mL 0.6611 mL 1.6528 mL
15 mM 0.0441 mL 0.2204 mL 0.4407 mL 1.1018 mL
20 mM 0.0331 mL 0.1653 mL 0.3306 mL 0.8264 mL
25 mM 0.0264 mL 0.1322 mL 0.2644 mL 0.6611 mL
30 mM 0.0220 mL 0.1102 mL 0.2204 mL 0.5509 mL
40 mM 0.0165 mL 0.0826 mL 0.1653 mL 0.4132 mL
50 mM 0.0132 mL 0.0661 mL 0.1322 mL 0.3306 mL
60 mM 0.0110 mL 0.0551 mL 0.1102 mL 0.2755 mL
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Bleomycin A2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bleomycin A241432-97-7Bleomycin A 2Bleomycin A-2Antibioticantitumor antibioticDNA-degradationAspHInhibitorinhibitorinhibit

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