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Amikacin hydrate

(Synonyms: BAY 41-6551 hydrate)
30 Cited Publications
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Based on 30 publication(s) in Google Scholar

Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria.

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  • Pureza : 99.43%
  • No. CAS: 1257517-67-1
  • Fòrmula: C22H43N5O13.xH2O
  • Almacenamiento:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Amikacin hydrate Chemical Structure
    Amikacin hydrate Chemical Structure
  • Experimental Validation Results for Amikacin hydrate
  • Experimental Validation Results for Amikacin hydrate
  • Experimental Validation Results for Amikacin hydrate
No. CAS: 1257517-67-1
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Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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  • Amikacin hydrate Chemical Structure
    Amikacin hydrate Chemical Structure
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    Amikacin hydrate purchased from MedChemExpress. Usage Cited in: J Antimicrob Chemother. 2026 Jun 3;81(7):dkag204. [Abstract]

    Customer Validation
     Checkerboard and time–kill analyses of antibiotic combinations under low-nutrient condition. Meropenem (128 mg/L, SMD) for 3 h and then Amikacin (1, 8, 32 mg/L, WMD) for 3 h.

  • 1/16

    Amikacin hydrate purchased from MedChemExpress. Usage Cited in: Eur J Clin Microbiol Infect Dis. 2025 Jun;44(6):1493-1500. [Abstract]

    Customer Validation
     MIC distributions of 22 P. aeruginosa clinical isolates (OXA-producing) in Amikacin (AMK) MICs in monotherapy and combination therapy with CZA and the probability of target attainment of a Cmax/MIC > 8 for AMK 25 mg/kg or 30 mg/kg dosing regimens. PTA: probability of target attainment.

  • 1/16

    Amikacin hydrate purchased from MedChemExpress. Usage Cited in: Int J Med Microbiol. 2023 Mar 28;313(2):151578. [Abstract]

    Customer Validation
     Time-growth and time-kill curves of S. aureus ATCC 43300 upon treatment with 1/4 × MIC aminoglycosides, including Amikacin (AMK, 8 µg/mL), gentamicin (GEN, 32 µg/mL), kanamycin (KANA, 16 µg/mL), and tobramycin (TOB, 32 µg/mL), in the presence or absence of HXS (4 µg/mL).

  • Amikacin hydrate