1. Anti-infection
  2. Bacterial Antibiotic
  3. Kasugamycin hydrochloride hydrate

Kasugamycin hydrochloride hydrate  (Synonyms: Ksg hydrochloride hydrate)

Cat. No.: HY-B1864B Purity: 99.76%
COA Handling Instructions

Kasugamycin hydrochloride hydrate (Ksg hydrochloride hydrate) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride hydrate (Ksg hydrochloride hydrate) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.

For research use only. We do not sell to patients.

Kasugamycin hydrochloride hydrate Chemical Structure

Kasugamycin hydrochloride hydrate Chemical Structure

CAS No. : 200132-83-8

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 44 In-stock
Solution
10 mM * 1 mL in Water USD 44 In-stock
Solid
500 mg USD 40 In-stock
1 g USD 60 In-stock
5 g   Get quote  
10 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Kasugamycin hydrochloride hydrate:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Kasugamycin hydrochloride hydrate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Kasugamycin hydrochloride hydrate (Ksg hydrochloride hydrate) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride hydrate (Ksg hydrochloride hydrate) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation[1][2].

Molecular Weight

433.84

Formula

C14H28ClN3O10

CAS No.
Appearance

Solid

Color

White to light brown

SMILES

OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.[H]Cl.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (57.62 mM; Need ultrasonic)

DMSO : 1.67 mg/mL (3.85 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3050 mL 11.5250 mL 23.0500 mL
5 mM 0.4610 mL 2.3050 mL 4.6100 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 8.33 mg/mL (19.20 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.76%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.3050 mL 11.5250 mL 23.0500 mL 57.6249 mL
H2O 5 mM 0.4610 mL 2.3050 mL 4.6100 mL 11.5250 mL
10 mM 0.2305 mL 1.1525 mL 2.3050 mL 5.7625 mL
15 mM 0.1537 mL 0.7683 mL 1.5367 mL 3.8417 mL
20 mM 0.1152 mL 0.5762 mL 1.1525 mL 2.8812 mL
25 mM 0.0922 mL 0.4610 mL 0.9220 mL 2.3050 mL
30 mM 0.0768 mL 0.3842 mL 0.7683 mL 1.9208 mL
40 mM 0.0576 mL 0.2881 mL 0.5762 mL 1.4406 mL
50 mM 0.0461 mL 0.2305 mL 0.4610 mL 1.1525 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Kasugamycin hydrochloride hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Kasugamycin hydrochloride hydrate
Cat. No.:
HY-B1864B
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