Kasugamycin hydrochloride hydrate (Standard)
Kasugamycin hydrochloride hydrate (Standard) (Ksg hydrochloride hydrate (Standard)) is the analytical standard of Kasugamycin hydrochloride hydrate (HY-B1864B). This product is intended for research and analytical applications. Kasugamycin (Ksg) hydrochloride hydrate is an aminoglycoside antibiotic (antibiotic) that binds to the bacterial 30S ribosomal subunit and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate binds to the P-site and E-site codon regions in the mRNA channel and interferes with mRNA-tRNA codon-anticodon interactions, thereby destabilizing initiator tRNA binding. Kasugamycin hydrochloride hydrate possesses anti-infective activity. Kasugamycin hydrochloride hydrate is used in research on bacterial translation and Pseudomonas infection.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 200132-83-8
- Formula: C14H28ClN3O10
- Molecular Weight:433.84
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 200132-83-8
-
Molecular Weight 433.84
-
Formula C14H28ClN3O10
-
SMILES
OC(C(N[C@@H](C[C@@H]1N)[C@@H](C)O[C@]1([H])O[C@@H]2[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@H]2O)=N)=O.[H]Cl.O
-
Synonyms
Ksg hydrochloride hydrate (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Zhang H, et al. Simultaneous determination of kasugamycin and validamycin-A residues in cereals by consecutive solid-phase extraction combined with liquid chromatography-tandem mass spectrometry. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2018 Mar;35(3):487-497. [Content Brief]
[2]. Schluenzen F, et al. The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nature structural & molecular biology. 2006 Oct;13(10):871-8. [Content Brief]
[3]. Kasuga K, et al. Heterologous production of kasugamycin, an aminoglycoside antibiotic from Streptomyces kasugaensis, in Streptomyces lividans and Rhodococcus erythropolis L-88 by constitutive expression of the biosynthetic gene cluster. Applied microbiology and biotechnology. 2017 May;101(10):4259-4268. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Kasugamycin hydrochloride hydrate (Standard) Related Classifications
HY-B1864BR Related Classifications
Powered by Bioz
Keywords
- Kasugamycin hydrochloride hydrate (Standard)
- 200132-83-8
- Ksg hydrochloride hydrate (Standard)
- Reference Standards
- Antibiotic
- Bacterial
- aminoglycoside antibiotic
- Magnaporthe oryzae
- 30S ribosomal subunit
- rice blast disease
- 16S rRNA
- Rhizoctonia solani
- translation initiation inhibitor
- Pseudomonas aeruginosa
- Rhizoctonia cerealis
- Streptomyces kasugaensis
- Inhibitor
- inhibitor
- inhibit