1. Metabolic Enzyme/Protease
  2. HIV Integrase
  3. Equisetin

Equisetin 

Cat. No.: HY-N6711
Handling Instructions

Equisetin is an N-methylserine-derived acyl tetramic acid isolated from a terrestrial fungus Fusarium equiseti NRRL 5537. Equisetin is a tetramate-containing natural product with antibiotic and cytotoxic activity. Equisetin inhibits the growth of Gram-positive bacteria and HIV-1 integrase activity but shows no activity against Gram-negative bacteria. Equisetin is a Quorum-sensing inhibitor (QSI) that attenuates QS-regulated virulence phenotypes in P. aeruginosa without affecting the growth of bacterias, serves as a leading compound for the treatment of P. aeruginosa infections.

For research use only. We do not sell to patients.

Equisetin Chemical Structure

Equisetin Chemical Structure

CAS No. : 57749-43-6

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Description

Equisetin is an N-methylserine-derived acyl tetramic acid isolated from a terrestrial fungus Fusarium equiseti NRRL 5537[1]. Equisetin is a tetramate-containing natural product with antibiotic and cytotoxic activity[2]. Equisetin inhibits the growth of Gram-positive bacteria and HIV-1 integrase activity but shows no activity against Gram-negative bacteria[3]. Equisetin is a Quorum-sensing inhibitor (QSI) that attenuates QS-regulated virulence phenotypes in P. aeruginosa without affecting the growth of bacterias, serves as a leading compound for the treatment of P. aeruginosa infections[4].

Molecular Weight

373.49

Formula

C₂₂H₃₁NO₄

CAS No.

57749-43-6

SMILES

O=C(/C1=C(O)\[[email protected]]2(C)[[email protected]](/C=C/C)C=C[[email protected]]3([H])C[[email protected]](C)CC[[email protected]@]23[H])N(C)[[email protected]@H](CO)C1=O

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Equisetin
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