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製品番号: HY-N6680

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Virginiamycin S1

(別名: Virginiamycin S)

1 Cited Publications

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Virginiamycin S1 (Virginiamycin S) is a streptogramin class B antibiotic. Virginiamycin S1 binds to the bacterial 50S ribosome, occupies the region near the P-site, induces tRNA misreading/stalling, inhibits peptide chain elongation, and exhibits synergistic activity against Gram-positive bacteria when used in combination with Virginiamycin M1 (HY-N6686). Virginiamycin S1 can be used in the research of Gram-positive bacterial infections.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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純度: 99.13%
CAS 番号: 23152-29-6
分子式: C₄₃H₄₉N₇O₁₀
分子量:823.89

保管条件:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Virginiamycin S1 構造式

CAS 番号: 23152-29-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Virginiamycin S1 (24 h) inactivation of visG in Streptomyces virginiae completely abolishes virginiamycin S1 production without affecting virginiamycin M1 production, and complementation with the full-length visG gene restores virginiamycin S1 production to wild-type levels^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 23152-29-6
性状 Solid
分子量 823.89
分子式 C₄₃H₄₉N₇O₁₀
Color White to yellow
SMILES

O=C1N2[C@](CC(CC2)=O)([H])C(N[C@@H](C3=CC=CC=C3)C(O[C@@H]([C@H](NC(C4=C(C=CC=N4)O)=O)C(N[C@H](CC)C(N5[C@](CCC5)([H])C(N(C)[C@H]1CC6=CC=CC=C6)=O)=O)=O)C)=O)=O
別名

Virginiamycin S
Structure Classification
- Antibiotics
- Macrolide Antibiotics
Initial Source
- Microorganisms
Streptomyces virginiae
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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SSRN

2026 Mar 3.

純度とドキュメンテーション

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純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (278 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Ningsih F, et al. VisG is essential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine. Microbiology. 2011 Nov;157(Pt 11):3213-20. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Virginiamycin S1

1 Cited Publications

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生物活性
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- 体外実験
化学情報
Publications (1)
純度とドキュメンテーション
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Virginiamycin S1

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