Virginiamycin S1
Based on 1 publication(s) in Google Scholar
Virginiamycin S1 (Virginiamycin S) is a streptogramin class B antibiotic. Virginiamycin S1 binds to the bacterial 50S ribosome, occupies the region near the P-site, induces tRNA misreading/stalling, inhibits peptide chain elongation, and exhibits synergistic activity against Gram-positive bacteria when used in combination with Virginiamycin M1 (HY-N6686). Virginiamycin S1 can be used in the research of Gram-positive bacterial infections.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.13%
- CAS. Nr.: 23152-29-6
- Formel: C43H49N7O10
- Molecular Weight:823.89
-
Speicherung:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Virginiamycin S1
More
Biologische Aktivität
Beschreibung
In Vitro
Virginiamycin S1 (24 h) inactivation of visG in Streptomyces virginiae completely abolishes virginiamycin S1 production without affecting virginiamycin M1 production, and complementation with the full-length visG gene restores virginiamycin S1 production to wild-type levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 23152-29-6
-
Appearance Solid
-
Molecular Weight 823.89
-
Formel C43H49N7O10
-
Color White to yellow
-
SMILES
O=C1N2[C@](CC(CC2)=O)([H])C(N[C@@H](C3=CC=CC=C3)C(O[C@@H]([C@H](NC(C4=C(C=CC=N4)O)=O)C(N[C@H](CC)C(N5[C@](CCC5)([H])C(N(C)[C@H]1CC6=CC=CC=C6)=O)=O)=O)C)=O)=O
-
Synonyms
Virginiamycin S
-
Structure Classification
-
Initial Source
Streptomyces virginiae
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
-
Journal Impact Factor
-
Most Recent
Reinheit & Dokumentation
-
Data Sheet (278 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)