23152-29-6
Chemical Structure
Virginiamycin S1
Synonym(s): Virginiamycin S
- CAS No.: 23152-29-6
- Formula:C43H49N7O10
- Molecular Weight:823.89
IUPAC Name: N-((6R,9S,10R,13S,15aS,22S,24aS)-22-benzyl-6-ethyl-10,23-dimethyl-5,8,12,15,17,21,24-heptaoxo-13-phenyldocosahydro-12H-pyrido[2,1-f]pyrrolo[2,1-l][1]oxa[4,7,10,13,16]pentaazacyclononadecin-9-yl)-3-hydroxypicolinamide
InChIKey: FEPMHVLSLDOMQC-IYPFLVAKSA-N
SMILES: O=C1N2[C@](CC(CC2)=O)([H])C(N[C@@H](C3=CC=CC=C3)C(O[C@@H]([C@H](NC(C4=C(C=CC=N4)O)=O)C(N[C@H](CC)C(N5[C@](CCC5)([H])C(N(C)[C@H]1CC6=CC=CC=C6)=O)=O)=O)C)=O)=O
Biological Activity: Virginiamycin S1 (Virginiamycin S) is a streptogramin class B antibiotic. Virginiamycin S1 binds to the bacterial 50S ribosome, occupies the region near the P-site, induces tRNA misreading/stalling, inhibits peptide chain elongation, and exhibits synergistic activity against Gram-positive bacteria when used in combination with Virginiamycin M1 (HY-N6686). Virginiamycin S1 can be used in the research of Gram-positive bacterial infections[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Virginiamycin S1 | 99.13% | Virginiamycin S1 (Virginiamycin S) is a streptogramin class B antibiotic. Virginiamycin S1 binds to the bacterial 50S ribosome, occupies the region near the P-site, induces tRNA misreading/stalling, inhibits peptide chain elongation, and exhibits synergistic activity against Gram-positive bacteria when used in combination with Virginiamycin M1 (HY-N6686). Virginiamycin S1 can be used in the research of Gram-positive bacterial infections. | ||||||||||||||||||||
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Virginiamycin S1 (Standard) | 99.02% | Virginiamycin S1 (Standard) is the analytical standard of Virginiamycin S1. This product is intended for research and analytical applications. Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections. | ||||||||||||||||||||
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Similarity Score 0.91
HY-105350Pristinamycin IB -
Similarity Score 0.91
HY-A0279APristinamycin IA -
Similarity Score 0.87
HY-N14891Pristinamycin ⅠC -
Similarity Score 0.83
HY-N14870Ostreogrycin B3 -
Similarity Score 0.75
HY-A0162Quinupristin -
Similarity Score 0.68
HY-N14494Neoviridogrisein Ⅰ -
Similarity Score 0.67
HY-N14861Neoviridogrisein Ⅱ -
Similarity Score 0.65
HY-112665Virginiamycin Complex -
Similarity Score 0.64
HY-N14863Neoviridogrisein III -
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