1. Anti-infection
  2. Bacterial

Nucleocidin (Synonyms: 4'-Fluoro-5'-O-sulfamoyladenosine; NSC 521007)

Cat. No.: HY-100496
Handling Instructions

Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein.

For research use only. We do not sell to patients.

Nucleocidin Chemical Structure

Nucleocidin Chemical Structure

CAS No. : 24751-69-7

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Nucleocidin is an antitrypanosomal antibiotic, inhibiting the transfer of labeled amino acid from S-RNA to protein.

IC50 & Target

Antibacterial[1].

In Vitro

Although appreciable inhibition occurrs at low concentrations of nucleocidin, it is not possible to obtain complete inhibition even at 10-3 M. An appreciable lag occurrs before any inhibition by nucleocidin is detectable, and the length of this lag period varies inversely with the concentration of nucleocidin. Similar results are obtained when nucleocidin is added to the cell-free system from reticulocytes. By contrast, essentially complete inhibition is obtained at 10-3 M puromycin, and only at the lowest concentrations is any lag detectable. It seems that nucleocidin exhibits the pattern typical of many antibiotics, i.e. it inhibits incorporation at a stage subsequent to the formation of aminoacyl-S-RNA[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7449 mL 13.7246 mL 27.4492 mL
5 mM 0.5490 mL 2.7449 mL 5.4898 mL
10 mM 0.2745 mL 1.3725 mL 2.7449 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

364.31

Formula

C₁₀H₁₃FN₆O₆S

CAS No.

24751-69-7

SMILES

O[[email protected]@H]([[email protected]]([[email protected]](N1C=NC2=C1N=CN=C2N)O3)O)[[email protected]@]3(F)COS(=O)(N)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Nucleocidin
Cat. No.:
HY-100496
Quantity:

Nucleocidin

Cat. No.: HY-100496