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  2. Bacterial
  3. Mupirocin calcium hydrate

Mupirocin calcium hydrate 

Cat. No.: HY-N7068
Handling Instructions

Mupirocin calcium hydrate is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium hydrate apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis.

For research use only. We do not sell to patients.

Mupirocin calcium hydrate Chemical Structure

Mupirocin calcium hydrate Chemical Structure

CAS No. : 115074-43-6

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Description

Mupirocin calcium hydrate is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium hydrate apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis[1][2].

In Vitro

Mupirocin Calcium Salt shows a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria. Mupirocin Calcium Salt is highly bound (95% bound) to the protein of human serum, and activity was reduced 10- to 20-fold in the presence of human serum[1].

In Vivo

Mupirocin Calcium Salt is well absorbed after oral and parenteral administration but serum antibiotic concentrations were short-lived as a result of extensive degradation to the antibacterially inactive metabolite, monic acid A[1].

Clinical Trial
Molecular Weight

538.68

Formula

C₂₆H₄₄O₉.₁/₂Ca.H₂O

CAS No.

115074-43-6

SMILES

C[[email protected]](O)[[email protected]](C)[[email protected]@]1([H])[[email protected]](C[[email protected]@]2([H])CO[[email protected]@H](C/C(C)=C/C(OCCCCCCCCC(O)=O)=O)[[email protected]](O)[[email protected]@H]2O)O1.[H]O[H].[1/2Ca]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Mupirocin calciumBacterialInhibitorinhibitorinhibit

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Mupirocin calcium hydrate
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HY-N7068
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