Acetomycin
Based on 1 Customer Validation
Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661.
For research use only. We do not sell to patients.
- Purity : 99.9%
- CAS No.: 510-18-9
- Formula: C10H14O5
- Molecular Weight:214.22
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All Antibiotic Isoforms
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Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
4 μM
Compound: 4a
|
Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay
Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay
|
10.1016/0960-894X(95)00110-F |
| DA-3 cell line | IC50 |
7 μM
Compound: 4a
|
Tested for cytotoxic activity against DA-3 mouse mammary adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against DA-3 mouse mammary adenocarcinoma cells in MTT assay
|
10.1016/0960-894X(95)00110-F |
| HT-29 | IC50 |
5 μM
Compound: 4a
|
Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay
|
10.1016/0960-894X(95)00110-F |
| MCF7 | IC50 |
6 μM
Compound: 4a
|
Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay
Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay
|
10.1016/0960-894X(95)00110-F |
Chemical Information
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CAS No. 510-18-9
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Appearance Solid
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Molecular Weight 214.22
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Formula C10H14O5
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Color White to off-white
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SMILES
O=C1O[C@@H](OC(C)=O)[C@@H](C)[C@]1(C(C)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)