1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Valnemulin Hydrochloride

Valnemulin Hydrochloride 

Cat. No.: HY-B0027 Purity: 99.84%
Handling Instructions

Valnemulin hydrochloride is a pleuromutilin antibiotic which inhibits protein synthesis in bacteria by binding the peptidyl transferase enzyme in the 50s ribosomal subunit.

For research use only. We do not sell to patients.

Valnemulin Hydrochloride Chemical Structure

Valnemulin Hydrochloride Chemical Structure

CAS No. : 133868-46-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
Estimated Time of Arrival: December 31
50 mg USD 70 In-stock
Estimated Time of Arrival: December 31
100 mg USD 110 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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Description

Valnemulin hydrochloride is a pleuromutilin antibiotic which inhibits protein synthesis in bacteria by binding the peptidyl transferase enzyme in the 50s ribosomal subunit.

Molecular Weight

601.28

Formula

C₃₁H₅₃ClN₂O₅S

CAS No.
SMILES

C[[email protected]@H]([[email protected]@H]([[email protected]@](C)(C[[email protected]]1OC(CSC(C)(C)CNC([[email protected]](N)C(C)C)=O)=O)C=C)O)C(CCC2=O)(CC[[email protected]]3C)[[email protected]]2([H])C31C.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (166.31 mM)

H2O : 100 mg/mL (166.31 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6631 mL 8.3156 mL 16.6312 mL
5 mM 0.3326 mL 1.6631 mL 3.3262 mL
10 mM 0.1663 mL 0.8316 mL 1.6631 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.16 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.16 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.16 mM); Clear solution

  • 4.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (166.31 mM); Clear solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

ValnemulinBacterialAntibioticInhibitorinhibitorinhibit

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Product Name:
Valnemulin Hydrochloride
Cat. No.:
HY-B0027
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