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  2. Bacterial
    Antibiotic
  3. Cephalexin (lysine)

Cephalexin (lysine) (Synonyms: Cefalexin (lysine); Cephacillin (lysine))

Cat. No.: HY-B0200D
Handling Instructions

Cephalexin (Cefalexin) lysine is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin lysine has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin lysine targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin lysine is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al.

For research use only. We do not sell to patients.

Cephalexin (lysine) Chemical Structure

Cephalexin (lysine) Chemical Structure

CAS No. : 53950-14-4

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Description

Cephalexin (Cefalexin) lysine is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin lysine has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin lysine targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin lysine is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1][2].

IC50 & Target

Bacteria[1]

In Vitro

Cephalexin lysine (10 μg/mL) disrupts polymer peptidoglycan (PG) biogenesis by inactivating enzymes called penicillin-binding proteins (PBPs)[1].
Cephalexin lysine inhibits a broad spectrum of grampositive and gram-negative organisms with MIC values of 2, 2, 2, 2, 4, 4.4 and 5.7 μg/mL for Bacillus anthracis, Edwardsiella taFda, Vibrio cholera, Pasteurella multocida, Edwardsiella tarda, Alcaligenes sp and Proteus rettgeri, respectively[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Cephalexin lysine (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss-Webster mice with infected bacterial[2]
Dosage: 0-50 mg/kg
Administration: Oral administration; for 3.5 hours
Result: Had antibacterial activity against Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus and several gram-negative species mice.
Molecular Weight

493.58

Formula

C22H31N5O6S

CAS No.
SMILES

O=C(C(N12)=C(C)CS[[email protected]]2([H])[[email protected]](NC([[email protected]](N)C3=CC=CC=C3)=O)C1=O)O.N[[email protected]](C(O)=O)CCCCN

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Cephalexin (lysine)
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