1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Cefsulodin sodium

Cefsulodin sodium 

Cat. No.: HY-13588 Purity: 97.27%
Handling Instructions

Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics.

For research use only. We do not sell to patients.

Cefsulodin sodium Chemical Structure

Cefsulodin sodium Chemical Structure

CAS No. : 52152-93-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 83 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 83 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 75 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics. Target: Antibacterial The compound displays a mechanism of action like many β lactam antibiotics through inhibition of cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) crosslinking of peptidoglycan resulting in inhibition of the final transpeptidation step. Through the inability for Cefsulodin sodium salt hydrate to inhibit cefsulodin-resistant mutants of Pseudomonas aeruginosa PAO4089 growth displayed that Cefsulodin sodium salt hydrate may compete with PBP3 in addtion to PBP1A and PBP1B.

Molecular Weight

554.53

Formula

C22H19N4NaO8S2

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 55 mg/mL (99.18 mM; Need ultrasonic)

DMSO : 13.5 mg/mL (24.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8033 mL 9.0166 mL 18.0333 mL
5 mM 0.3607 mL 1.8033 mL 3.6067 mL
10 mM 0.1803 mL 0.9017 mL 1.8033 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.25 mg/mL (4.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.25 mg/mL (4.06 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.75 mM); Clear solution

*All of the co-solvents are available by MCE.
References

Purity: 97.27%

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Product Name:
Cefsulodin sodium
Cat. No.:
HY-13588
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