MBL-IN-2
MBL-IN-2 ((2R, 2R')-5αC) is an inhibitor of Metallo-β-lactamase (MBL) that can inhibit New Delhi Metallo-β-lactamase-1 (NDM-1) with an IC50 of 0.3 μM. MBL-IN-2 ((2R, 2R')-5αC) can be used for the study of resistance to β-lactam antibiotics.
For research use only. We do not sell to patients.
- CAS No.: 3058802-26-6
- Formula: C9H12F3NO3S
- Molecular Weight:271.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Beta-lactamase Isoforms
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Biological Activity
Description
IC50 & Target
IC50:0.3 μM (NDM-1)[1].
Chemical Information
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CAS No. 3058802-26-6
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Molecular Weight 271.26
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Formula C9H12F3NO3S
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SMILES
SC[C@@H](C(F)(F)F)C(N1CCC[C@@H]1C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)