Aurachin D
Based on 1 Customer Validation
Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles.
For research use only. We do not sell to patients.
- Purity: 99.55%
- CAS No.: 108354-13-8
- Formula: C25H33NO
- Molecular Weight:363.54
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Antibiotic Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L929 | IC50 |
1.3 μg/mL
Compound: 3
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Cytotoxicity against mouse L929 cells after 5 days by MTT assay
Cytotoxicity against mouse L929 cells after 5 days by MTT assay
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[PMID: 18922036] |
Chemical Information
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CAS No. 108354-13-8
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Appearance Solid
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Molecular Weight 363.54
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Formula C25H33NO
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Color White to light brown
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SMILES
O=C1C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C(C)NC2=C1C=CC=C2
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Structure Classification
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Initial Source
myxobacteria
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (137.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7507 mL | 13.7536 mL | 27.5073 mL | 68.7682 mL |
| 5 mM | 0.5501 mL | 2.7507 mL | 5.5015 mL | 13.7536 mL | |
| 10 mM | 0.2751 mL | 1.3754 mL | 2.7507 mL | 6.8768 mL | |
| 15 mM | 0.1834 mL | 0.9169 mL | 1.8338 mL | 4.5845 mL | |
| 20 mM | 0.1375 mL | 0.6877 mL | 1.3754 mL | 3.4384 mL | |
| 25 mM | 0.1100 mL | 0.5501 mL | 1.1003 mL | 2.7507 mL | |
| 30 mM | 0.0917 mL | 0.4585 mL | 0.9169 mL | 2.2923 mL | |
| 40 mM | 0.0688 mL | 0.3438 mL | 0.6877 mL | 1.7192 mL | |
| 50 mM | 0.0550 mL | 0.2751 mL | 0.5501 mL | 1.3754 mL | |
| 60 mM | 0.0458 mL | 0.2292 mL | 0.4585 mL | 1.1461 mL | |
| 80 mM | 0.0344 mL | 0.1719 mL | 0.3438 mL | 0.8596 mL | |
| 100 mM | 0.0275 mL | 0.1375 mL | 0.2751 mL | 0.6877 mL |