1. Apoptosis
    Autophagy
  2. Apoptosis
    Autophagy
  3. Calcimycin

Calcimycin (Synonyms: A23187)

Cat. No.: HY-N6687 Purity: >98.0%
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Calcimycin (A23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation of mammalian cells. It induces apoptosis.

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Calcimycin Chemical Structure

Calcimycin Chemical Structure

CAS No. : 52665-69-7

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10 mM * 1 mL in DMSO USD 253 In-stock
Estimated Time of Arrival: December 31
1 mg USD 75 In-stock
Estimated Time of Arrival: December 31
5 mg USD 220 In-stock
Estimated Time of Arrival: December 31
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Description

Calcimycin (A23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). It induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation of mammalian cells. It induces apoptosis[1][2][3][4].

Molecular Weight

523.62

Formula

C₂₉H₃₇N₃O₆

CAS No.

52665-69-7

SMILES
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Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >98.0%

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Calcimycin
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