2. Others Cell Cycle/DNA Damage Autophagy Anti-infection Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Antibiotic Endogenous Metabolite
  4. Berberine-d6 chloride

Berberine-d6 chloride  (Synonyms: Natural Yellow 18-d6 chloride)

Cat. No.: HY-18258S
Handling Instructions Technical Support

Berberine-d6 (chloride) is the deuterium labeled Berberine chloride. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties.

For research use only. We do not sell to patients.

Berberine-d<sub>6</sub> chloride

Berberine-d6 chloride Chemical Structure

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1 mg In-stock
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Other Forms of Berberine-d6 chloride:

Berberine-d6 chloride Related Antibodies

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Human Endogenous Metabolite Microbial Metabolite

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Description

Berberine-d6 (chloride) is the deuterium labeled Berberine chloride. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Berberine-d6 chloride Related Antibodies
Molecular Weight

377.85

Formula

C20H12D6ClNO4
Unlabeled CAS
SMILES

[2H]C([2H])([2H])OC1=C(OC([2H])([2H])[2H])C2=C[N+]3=C(C4=CC5=C(C=C4CC3)OCO5)C=C2C=C1.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : ≥ 52 mg/mL (137.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6466 mL 13.2328 mL 26.4655 mL
5 mM 0.5293 mL 2.6466 mL 5.2931 mL
View the Complete Stock Solution Preparation Table

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6466 mL 13.2328 mL 26.4655 mL 66.1638 mL
5 mM 0.5293 mL 2.6466 mL 5.2931 mL 13.2328 mL
10 mM 0.2647 mL 1.3233 mL 2.6466 mL 6.6164 mL
15 mM 0.1764 mL 0.8822 mL 1.7644 mL 4.4109 mL
20 mM 0.1323 mL 0.6616 mL 1.3233 mL 3.3082 mL
25 mM 0.1059 mL 0.5293 mL 1.0586 mL 2.6466 mL
30 mM 0.0882 mL 0.4411 mL 0.8822 mL 2.2055 mL
40 mM 0.0662 mL 0.3308 mL 0.6616 mL 1.6541 mL
50 mM 0.0529 mL 0.2647 mL 0.5293 mL 1.3233 mL
60 mM 0.0441 mL 0.2205 mL 0.4411 mL 1.1027 mL
80 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.8270 mL
100 mM 0.0265 mL 0.1323 mL 0.2647 mL 0.6616 mL
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Berberine-d6 chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Berberine-d6Natural Yellow 18-d6Isotope-Labeled CompoundsTopoisomeraseAutophagyBacterialReactive Oxygen Species (ROS)AntibioticEndogenous MetaboliteInhibitorinhibitorinhibit

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