1. Metabolic Enzyme/Protease
    Anti-infection
  2. HIV Protease
    Fungal
  3. Cytochalasin A

Cytochalasin A 

Cat. No.: HY-N6773
Handling Instructions

Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives.

For research use only. We do not sell to patients.

Cytochalasin A Chemical Structure

Cytochalasin A Chemical Structure

CAS No. : 14110-64-6

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Description

Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives[1][2].

IC50 & Target

HIV-1 protease[1]

Molecular Weight

477.59

Formula

C₂₉H₃₅NO₅

CAS No.

14110-64-6

SMILES

C[[email protected]@H]([[email protected]@]([[email protected]@]12[[email protected]](/C=C/C[[email protected]](C)CCCC(/C=C/C(O1)=O)=O)([H])[[email protected]@H]3O)([H])[[email protected]@H](NC2=O)CC4=CC=CC=C4)C3=C

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Room temperature in continental US; may vary elsewhere

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Cytochalasin A
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